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Intermittent Claudication

When taking a walk leaves you in pain, a hardening of the leg arteries may be the reason. According to research or other evidence, the following self-care steps may be helpful.
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

SupplementAmountWhy
Ginkgo
120 to 160 mg daily3 stars[3 stars]
Studies have reported that people with intermittent claudication see improvements in pain-free walking distance when supplementing with ginkgo.
Inositol Hexaniacinate (Vitamin B3)
2 grams twice per day3 stars[3 stars]
Inositol hexaniacinate, a special form of vitamin B3, has been used successfully to reduce symptoms, this treatment should be monitored by a doctor.
Policosanol
10 mg twice per day3 stars[3 stars]
Supplementing with policosanol may reduce platelet stickiness and improve walking capacity.
Propionyl-L-Carnitine
2 grams daily3 stars[3 stars]
In double-blind trials, supplementing with either L-carnitine or propionyl-L-carnitine (a form of L-carnitine) has increased walking distance in people with intermittent claudication.
Vitamin E
400 to 600 IU daily3 stars[3 stars]
Taking vitamin E may improve blood flow and increase walking capacity.
Fish Oil, Vitamin B6, Folic Acid, Vitamin E, Oleic Acid, and Alpha-Linolenic Acid
200 mg of EPA and 130 mg of DHA daily, plus small amounts of vitamin B6, folic acid, vitamin E, oleic acid, and alpha-linolenic acid2 stars[2 stars]
In one study, men with intermittent claudication who drank a milk product fortified with fish oil, vitamin B6, folic acid, vitamin E, oleic acid, and alpha-linolenic acid could walk further without pain than those who drank regular milk.
Garlic
400 mg of a standardized extract twice per day2 stars[2 stars]
In one study, people given a garlic powder extract could walk a significantly greater distance than those given a placebo.
L-Carnitine
2 grams a day of proprionyl-L-carnitine2 stars[2 stars]
In double-blind trials, supplementation with either L-carnitine or propionyl-L-carnitine (a form of L-carnitine) has increased walking distance in people with intermittent claudication.
Padma 28
760 mg twice per day2 stars[2 stars]
In one trial, people with intermittent claudication who took the Tibetan herbal formula Padma 28 increased their walking distance by an average of 115%.
Evening Primrose Oil
Refer to label instructions 1 star[1 star]
In a preliminary trial, supplementing with evening primrose oil led to a 10% increase in exercise tolerance in people with intermittent claudication.
Magnesium
Refer to label instructions 1 star[1 star]
Magnesium may increase blood flow by helping to dilate blood vessels. One trial found that taking magnesium may increase walking distance in people with intermittent claudication.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

 
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