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High Cholesterol

Also indexed as:Cholesterol (High), Dyslipidemia, Hypercholesterolemia, Hyperlipidemia, Hypoalphalipoproteinemia, Low HDL Cholesterol, LDL Cholesterol Damage, HDL Cholesterol Damage
Take control of your cholesterol to lower your heart disease risk. According to research or other evidence, the following self-care steps may be helpful.
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

2,900 to 15,000 mg daily3 stars[3 stars]
Beta-glucan is a type of soluble fiber that has been shown to lower total and LDL ("bad") cholesterol and raise HDL ("good") cholesterol.
200 to 500 mcg daily3 stars[3 stars]
Chromium supplementation has reduced total cholesterol and LDL cholesterol and increased HDL cholesterol in double-blind and other controlled trials.
10 to 30 grams three times per day with meals3 stars[3 stars]
Fenugreek seeds contain compounds that inhibit both cholesterol absorption in the intestines and cholesterol production by the liver.
4 to 13 grams daily3 stars[3 stars]
Glucomannan is a water-soluble dietary fiber that has been shown to significantly reduce total blood cholesterol, LDL cholesterol, and triglycerides, and to raise HDL cholesterol.
3 grams daily3 stars[3 stars]
Supplementing with HMB, or beta hydroxy-beta-methylbutyrate, is an effective way to lower total and LDL cholesterol.
Pantothenic Acid
300 mg pantethine taken two to four times per day3 stars[3 stars]
Pantethine, a byproduct of vitamin B5 (pantothenic acid), may help reduce the amount of cholesterol made by the body.
5 to 10 grams per day with meals3 stars[3 stars]
Psyllium has been shown to be effective at lowering total and LDL ("bad") cholesterol.
Red Yeast Rice
1.2 to 2.4 grams (5 to 10 mg of monacolins) daily in divided amounts3 stars[3 stars]
One of the ingredients in red yeast rice appears to block the production of cholesterol in the liver.
1.7 grams daily3 stars[3 stars]
Sitostanol, a synthetic molecule related to beta-sitosterol, is available in margarine form and has also been shown to lower cholesterol levels.
25 grams soy protein per day3 stars[3 stars]
Soy supplementation has been shown to lower cholesterol. Soy contains isoflavones, which are believed to be soy's main cholesterol-lowering ingredients.
Vitamin B3 (Niacin)
1,500 to 3,000 mg daily under a doctor's supervision3 stars[3 stars]
High amounts (several grams per day) of niacin, a form of vitamin B3, have been shown to lower cholesterol.
Vitamin C
1,000 mg daily3 stars[3 stars]
Vitamin C appears to protect LDL cholesterol from damage, and in some trials, cholesterol levels have fallen when people supplement with vitamin C.
Refer to label instructions 2 stars[2 stars]
Artichoke has moderately lowered cholesterol and triglycerides in some trials.
4 to 12 mg daily2 stars[2 stars]
Astaxanthin has antioxidant and other properties that may help improve blood cholesterol regulation and protect against lipoprotein oxidation.
15 to 20 drops of tincture twice per day for six months2 stars[2 stars]
In one trial, people who took a tincture of Achillea wilhelmsii had significant reductions in total cholesterol, LDL cholesterol, and triglycerides and an increase in HDL cholesterol.
500 mg twice per day2 stars[2 stars]
Berberine, a compound found in certain herbs such as goldenseal, barberry, and Oregon grape, has been found to lower serum cholesterol levels.

(Type 2 Diabetes)
500 mg of berberine taken twice a day for three months2 stars[2 stars]
Berberine, a compound found in certain herbs such as goldenseal, barberry, and Oregon grape, has been found to lower serum cholesterol levels.
0.8 to 3.2 grams daily 2 stars[2 stars]
Beta-sitosterol blocks cholesterol absorption and has been shown in studies to reduce blood levels of cholesterol.
800 to 1,000 mg daily2 stars[2 stars]
Some trials have shown that supplementing with calcium reduces cholesterol levels.
4 to 32 grams per day 2 stars[2 stars]
Activated charcoal has the ability to attach (adsorb) cholesterol and bile acids present in the intestine, preventing their absorption.
3 to 4 mg daily2 stars[2 stars]
Copper deficiency has been linked to high blood cholesterol, supplementing with it may correct a deficiency and lower cholesterol.
500 mg three times per day after meals 2 stars[2 stars]
Supplementing with a cranberry extract has been shown to help lower total and LDL ("bad") cholesterol in people with type 2 diabetes taking hypoglycemic medication.
600 to 900 mg a day of a standardized herbal extract2 stars[2 stars]
Taking garlic may help lower cholesterol and prevent hardening of the arteries.
Green Tea
3 cups daily2 stars[2 stars]
Green tea has been shown to lower total cholesterol levels and improve people's cholesterol profile.
Green Tea Enriched with Theaflavins
75 mg of theaflavins, 150 mg of green tea catechins, and 150 mg of other tea polyphenols daily2 stars[2 stars]
An extract of green tea, enriched with a compound present in black tea (theaflavins), has been found to lower serum cholesterol in people with moderately high cholesterol levels.
25 mg guggulsterones three times per day2 stars[2 stars]
Guggul appears to be helpful in lowering cholesterol and raising HDL ("good") cholesterol.
Inositol Hexaniacinate (Vitamin B3)
500 to 1,000 mg of inositol hexaniacinate three times daily under medical supervision2 stars[2 stars]
Inositol hexaniacinate, a special form of vitamin B3, has been reported to lower serum cholesterol, and apparently without the toxicity of high levels of niacin.
Krill Oil
1 to 3 grams krill oil daily2 stars[2 stars]
In one study of people with high cholesterol or triglycerides, supplementing with krill oil lowered total cholesterol, LDL cholesterol, and triglycerides, and increased HDL-cholesterol.
Royal Jelly
50 to 100 mg daily2 stars[2 stars]
Supplementing with royal jelly may lower cholesterol levels.
200 mg daily2 stars[2 stars]
Tocotrienols may lower cholesterol levels. Tocotrienols inhibited cholesterol synthesis in test-tube studies, and two trials found that tocotrienols reduced cholesterol levels by 13-15%.
Refer to label instructions 1 star[1 star]
Saponins in alfalfa seeds may block cholesterol absorption and prevent the formation of atherosclerotic plaques.
Refer to label instructions 1 star[1 star]
Chitosan is a fiber-like supplement that has been shown to lower cholesterol and raise HDL ("good") cholesterol).
Chondroitin Sulfate
Refer to label instructions 1 star[1 star]
Chondroitin sulfate has lowered serum cholesterol levels in preliminary trials.
Creatine Monohydrate
Refer to label instructions 1 star[1 star]
One trial found that supplementing with creatine significantly lowered serum total cholesterol and triglycerides in people with high cholesterol.
Refer to label instructions 1 star[1 star]
Preliminary Chinese research has found that high doses of the herb fo-ti may lower cholesterol levels.
Refer to label instructions 1 star[1 star]
Some preliminary trials report that L-carnitine reduces serum cholesterol and raises HDL cholesterol.
Lecithin (Phosphatidyl Choline)
Refer to label instructions 1 star[1 star]
Taking lecithin supplements may be a useful way to lower cholesterol.
Refer to label instructions 1 star[1 star]
In a preliminary study, magnesium supplementation lowered total cholesterol and increased HDL ("good") cholesterol levels.
Refer to label instructions 1 star[1 star]
The mushroom maitake may lower fat levels in the blood and be useful in lowering cholesterol.
Refer to label instructions 1 star[1 star]
Policosanol may affect cholesterol levels by inhibiting cholesterol production by the liver but most research has casted doubt on its effectiveness.
150 mg per day 1 star[1 star]
Preliminary research suggests that Pycnogenol may lower LDL cholesterol and raise HDL cholesterol in people with normal cholesterol levels.
Sea Buckthorn
Refer to label instructions 1 star[1 star]
Sea buckthorn contains flavonoids and essential fatty acids that may influence blood cholesterol according to animal and preliminary human research.
Refer to label instructions 1 star[1 star]
A double-blind trial found that, in people with moderately elevated cholesterol levels, supplementing with selenium in the form of high-selenium yeast resulted in a small but statistically significant decrease in serum cholesterol.
Vitamin E
Refer to label instructions 1 star[1 star]
In one trial, supplementing with vitamin E increased levels of protective HDL cholesterol.
Wild Yam
Refer to label instructions 1 star[1 star]
Wild yam has been reported to raise HDL ("good") cholesterol in preliminary research.

Copyright 2015 Aisle7. All rights reserved.

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Learn more about the authors of Aisle7 products.

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2016.

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