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Insulin Resistance Syndrome

Also indexed as:Syndrome X, Metabolic Syndrome
Reduce your insulin-resistance risk by focusing on diet and lifestyle. According to research or other evidence, the following self-care steps may be helpful.
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by some in the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

SupplementAmountWhy
Glucomannan
8 to 13 grams daily3 stars[3 stars]
Taking a glucomannan fiber supplement may improve blood cholesterol and blood sugar.
Chromium
200 mcg daily2 stars[2 stars]
Supplementing with chromium may help improve the action of insulin.
Guar Gum
30 grams daily2 stars[2 stars]
One study of healthy people found that guar gum, a fiber similar to glucomannan, improved insulin sensitivity and many other components of IRS.
Calcium
Refer to label instructions 1 star[1 star]
One study found that supplementing with calcium improved insulin sensitivity in people with hypertension.
Coenzyme Q10
Refer to label instructions 1 star[1 star]
Coenzyme Q10 may improve insulin sensitivity in people with components of IRS.
Magnesium
Refer to label instructions 1 star[1 star]
Magnesium deficiency can reduce insulin sensitivity, and low magnesium levels have been associated with greater insulin resistance in nondiabetic people, leading some doctors to believe that supplementing with magnesium may improve IRS.
Vitamin E
Refer to label instructions 1 star[1 star]
Vitamin E has been shown to increase insulin sensitivity in both healthy and hypertensive people and may have a similar effect on people with IRS.
Zinc
Refer to label instructions 1 star[1 star]
Low zinc intake appears to be associated with several of the risk factors common in IRS, and a low blood level of zinc is associated with insulin resistance in overweight people.

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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.