When the weather shifts from summer’s warmth to the chill of fall, many of us turn our attention to supporting our immune systems. While we might consider a range of supplements and herbal remedies to support our defenses—elderberry, vitamin D, and turmeric, for example—one lesser-known herb stands out as a powerful ally in immune preparation: astragalus. This remarkable herb, known as a “deep immune builder,” offers a unique approach to supporting our bodies during the colder months and equipping our defenses with the foundation needed to fend off potential germs and immune challenges.
Ahead, learn more about astragalus’ unique benefits and why it makes an excellent addition to your winter wellness routine.
What Is Astragalus—and How Does It Work?
Astragalus, scientifically known as Astragalus membranaceus (and also called huáng qí and milkvetch), is an herb with a rich history in traditional Chinese medicine, where it has been utilized for thousands of years, according to Dr. Joshua Axe, D.N.M., C.N., N.M.D., a doctor of natural medicine, nutritionist, and the founder of Ancient Nutrition.
Revered for its adaptogenic properties, astragalus is thought to “enhance the body’s overall balance and resilience to stress,” including physical, emotional, and environmental stressors, Axe says. However, “its effects on the immune system are astragalus’ claim to fame.”
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According to the National Center for Complimentary and Integrative Health, this herb has traditionally been used to support upper-respiratory health, balanced immunity amidst allergens, wound healing, healthy blood flow, and overall energy production. Studies show it supports renal (kidney) health, too.
How It Helps Support and Prepare the Immune System
The root of the astragalus plant is the part typically used in herbal medicine, as it’s packed with beneficial compounds, including polysaccharides, flavonoids, and saponins (the same types found in superfoods and herbs like kale, mushrooms, seaweed, and ginseng).
The way that astragalus works in the body is multifaceted. One of its primary actions is to stimulate the production of immune cells, including T cells and macrophages, which play crucial roles in the immune response. By enhancing the activity of these cells, it can help the body better recognize and respond to offenders.
“Astragalus is great for balancing TH1/TH2 cells,” says Axe. These helper cells are vital for a properly functioning immune system. In fact, imbalances in TH1 and TH2 can contribute to allergies, autoimmunity, and chronic illnesses, according to to Dr. Chelsea Azarcon, N.M.D.
Additionally, research suggests astragalus can modify pathways that lead to inflammation and increase telomerase activity, which prolongs the lifespan of cells and may help defend against dysfunction that contributes to chronic health issues.
And lastly, the super-herb is known to have powerful antioxidant properties, aiding in the reduction of oxidative stress and free radical damage that impair immune function and can exacerbate symptoms of illnesses and health conditions. Indeed, Axe and many other experts believe that, thanks to its saponins and polysaccharides, as well as its prebiotics, astragalus is a meaningful ally for those managing chronic health issues.
The Difference Between Astragalus And Other Immune Herbs
What sets astragalus apart from many other immune-supporting herbs and supplements is its role as a preventative measure rather than a reactive one. In other words, herbalists often recommend taking astragalus long-term, specifically when you are feeling well, to “prep” your immune foundation for anything that might come your way.
“Unlike other types of adaptogenic herbs which can generally be taken regardless of whether or not there’s an acute illness present, traditional folk herbalists and clinical herbalists recommend only taking astragalus as a preventive herb for immunity and wellness,” explains functional dietitian and clinical herbalist Jenna Volpe, R.D.N., L.D., C.L.T.
For example, astragalus might be helpful when taken for the month or so before children return to school, for a few weeks before pollen season, or throughout the fall and winter. This approach can help promote a balanced, strong immune system capable of responding to anything that comes its way during the school year, allergy season, or the colder months.
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The rationale behind this strategy lies in the herb’s ability to “prime” the immune system. By supporting the body’s innate defenses, astragalus helps your system create a robust barrier against offenders, according to Volpe. Unlike some herbs that may stimulate the immune system aggressively when needed, astragalus works quietly and effectively to support the immune system over time while one is healthy.
Interestingly, it’s sometimes advised that you stop taking astragalus if you do become ill. “Astragalus’ mechanisms aren’t entirely understood, but anecdotally, and per a small clinical case study, astragalus seems to alter (upregulate and downregulate) immune system pathways in such a way that can increase cytokines, a type of chemical mediator,” explains Volpe. “While this can actually support someone who is currently well, it isn’t ideal for somebody who is already sick.”
How to Use Astragalus Safely And Effectively
Astragalus is available in various forms, including capsules, powders, and teas. Sourcing from a reputable supplier is the best way to ensure you’re receiving a high-quality product.
In terms of dosage, “in the field of Traditional Chinese Medicine and Western clinical herbalism, astragalus extracts of 1,000 to 3,000 milligrams (one to three grams) may be recommended up to three times daily,” Volpe says. “This generally translates to about one to three cups of astragalus root tea decoctions daily (about two teaspoons of dried and chopped astragalus root per 12 ounces water) or about two to four milliliters (or 40 to 80 drops) of astragalus root tincture up to three times daily.” You can incorporate astragalus into your routine in these ways for months at a time, provided you’re feeling well.
Of course, it’s vital to listen to your body. If you start taking astragalus and notice an adverse reaction, such as diarrhea, upset stomach, or signs of an allergy like a rash that doesn’t resolve, discontinue use or consult a healthcare professional. Again, you’ll also want to cease use when under the weather, reminds Volpe.
Astragalus can potentially interact with certain medications, such as immunosuppressants (which also impact immune function). Anyone taking medications—including those used to manage immune function, blood pressure, or blood clotting—should seek medical advice before trying this herb.




