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5-HTP with Vitamin B6 for Mood Support - 100 MG (120 Capsules)

5-HTP with Vitamin B6 for Mood Support - 100 MG (120 Capsules)

$34.99
($0.29/serving)

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5-HTP with Vitamin B6 for Mood Support - 100 MG (120 Capsules)

Rated 4.3 out of 5
16 Reviews|7 Questions | 200 Answers|
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    Main Product
      Gluten FreeDairy FreeSoy FreeTree Nut Free
      GET ADVICE FROM A HEALTH ENTHUSIAST
      $34.99
      ($0.29/serving)

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      • 100 MG
      • 120 Capsules$34.99
      • 60 Capsules$19.99
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      5-HTP with Vitamin B6 for Mood Support - 100 MG (120 Capsules)
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      Slide 1 of 3

      Product Info

      About This Product

      • Provides mood support
      • Free of gluten, dairy, soy, nuts, sugar, salt, preservatives, and artificial colors or flavors

      We all need a little pick-me-up from time to time. Designed to support a positive mood, The Vitamin Shoppe® brand 5-HTP with Vitamin B6 is a great go-to when you're experiencing the occasional blues.

      This feel-good formula features 5-hydroxytryptophan—which gets converted into serotonin in the brain, and vitamin B6—which is required for making neurotransmitters like serotonin.

      Read More

      Directions

      Take one (1) capsule daily, preferably in between meals.

      Warning

      Do not use this product if you are pregnant or nursing or taking any antidepressant medications such as selective serotonin reuptake inhibitors (SSRI's), tricyclic antidepressants or monamine oxidase inhibitors (MAOI). Consult your physician prior to use if you have any medical condition or are taking any medications. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

      Updated Jan 15, 2026
      Read More

      Supplement Facts

      Serving Size: 1 Capsule
      Number of Servings: 120 Servings
      Amount Per Serving
      % Daily Value
      VITAMIN B6  - (FROM PYRIDOXINE HCI)
      20 MG
      1176%
      CALCIUM  - (AS CALCIUM PHOSPHATE)
      70 MG
      5%
      PHOSPHORUS  - (AS DICALCIUM PHOSPHATE)
      54 MG
      4%
      5-HYDROXYTRYPTOPHAN  - (FROM GRIFFONIA SIMPLICIFOLIA) (SEED)
      100 MG
      N/A*

      Other Ingredients:

      Microcrystalline cellulose, gelatin, magnesium stearate, silicon dioxide.

      How Do You Read A Supplement Facts Label?

      Specifications

      Brand:
      The Vitamin Shoppe
      Form:
      Capsules
      Strength:
      100 MG
      Serving Size:
      1 Capsule
      Number of Servings:
      120 Servings
      Price per Serving:
      ($0.29 / serving)
      Product Weight:
      4  OZ
      Allergens:
      Soy Free, Tree Nut Free
      Specialty Diets:
      Gluten Free ,  Dairy Free
      Item # :
      VS-2284 / 1723451

      Product Reviews
         (16)

      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      16 Ratings
      4.3out of 5 stars
      16 Ratings

      Rated 5 stars by 69% of reviewers

      569%

      Rated 4 stars by 12% of reviewers

      412%

      Rated 3 stars by 6% of reviewers

      36%

      Rated 2 stars by 6% of reviewers

      26%

      Rated 1 star by 6% of reviewers

      16%
      1-10 of 16 Reviews
      • checkMost Recent
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      • (11)
      • (2)
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      • (1)
      • (1)
      • Under 18 (0)
      • 18-24 (1)
      • 25-34 (1)
      • 35-44 (3)
      • 45-54 (3)
      • 55-64 (0)
      • 65+ (3)
      Mar 31, 2026
      Rated 3 out of 5
      My honest review
      It's ok, it's better take at night due to the sleepy effect it gives off. If u take in the morning you may feel very tired throughout the day. It can cause headaches. I started off with 100mg I recommend starting with 50mg for beginners. Haven't really seen improvement yet. But it's good for nigh time if u have trouble sleeping
      Zack BVerified Purchaser
      Location
      Long Island, NY, US
      Gender
      Male
      Age Range
      18-24
      Would you recommend?:Yes
      Purchased on Jan 11, 2026
      Was this helpful?
      Review by Zack B has been flagged
      Flag
      Jan 19, 2025
      Rated 5 out of 5
      Works well for mild depression or PMS
      I found this helpful for depression symptoms and much more effective than SAMe.
      Emerald NVerified Purchaser
      Location
      CA, US
      Gender
      Female
      Age Range
      35-44
      Would you recommend?:Yes
      Purchased on Aug 10, 2017
      Was this helpful?
      Review by Emerald N has been flagged
      Flag
      Aug 27, 2024
      Rated 1 out of 5
      Major ACNE BREAKOUT!
      This made my face breakout like crazy. I believe that the 1176% daily value of vitamin B6 is the culprit.
      Jonathan S
      Location
      New York, NY, US
      Gender
      Male
      Age Range
      35-44
      Would you recommend?:No
      Was this helpful?
      Review by Jonathan S has been flagged
      Flag
      Oct 24, 2023
      Rated 5 out of 5
      Feel good be happy
      This is a must to deal with stress make you feel happy and help you go to sleep at night. I also like to take it with my coffee in the morning with some extra taurine.
      JORGE SVerified Purchaser
      Location
      Miami, FL, US
      Gender
      Male
      Age Range
      45-54
      Would you recommend?:Yes
      Purchased on Apr 14, 2018
      Was this helpful?
      Review by JORGE S has been flagged
      Flag
      Sep 20, 2023
      Rated 2 out of 5
      Not for people prone to acne due to b6
      Been taking it for a few months. Was helping my mood. But my face has been breaking out for the same duration. I tried looking at everything as to why and just noticed today the absurd amount of b6 in this. Since im not choosing between mood and acne, which brings my mood down anyway, my half full bottle and new bottle are going to be trashed
      Chris PVerified Purchaser
      Age Range
      25-34
      Would you recommend?:Yes
      Purchased on Aug 1, 2023
      Was this helpful?
      Review by Chris P has been flagged
      Flag
      Sep 19, 2023
      Rated 5 out of 5
      helpful
      Like the size and quality
      Beth ZVerified Purchaser
      Purchased on Aug 12, 2023
      Was this helpful?
      Review by Beth Z has been flagged
      Flag
      Feb 18, 2023
      Rated 5 out of 5
      It works
      I bought it to take with my Zoloft for that reason xtra boost of seratonin and it works
      JedenaVerified Purchaser
      Purchased on Jan 11, 2023
      Was this helpful?
      Review by Jedena has been flagged
      Flag
      Jul 21, 2020
      Rated 5 out of 5
      5 HTP with Vit B6
      Works fine....
      Ronald MVerified Purchaser
      Location
      Carol Stream , IL, US
      Gender
      Male
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Jun 2, 2020
      Was this helpful?
      Review by Ronald M has been flagged
      Flag
      Jul 14, 2020
      Rated 5 out of 5
      Prompt delivery
      Accurate product, amazingly prompt delivery.
      CATHLEEN GVerified Purchaser
      Location
      Shoreline, WA, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Apr 21, 2020
      Was this helpful?
      Review by CATHLEEN G has been flagged
      Flag
      Oct 11, 2019
      Rated 5 out of 5
      Its good
      I like these medicine works good
      Nathalie GVerified Purchaser
      Location
      Lakeland, FL, US
      Gender
      Female
      Age Range
      45-54
      Would you recommend?:Yes
      Purchased on Sep 11, 2019
      Was this helpful?
      Review by Nathalie G has been flagged
      Flag
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      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      3 Questions
      Why did you choose this?
      The Vitamin ShoppeStore

      Husband says it works for him.

      Janna CAug 29, 2026

      HELPS WITH SLEEP AND MOOD TAKING FOR YEARS

      BARBARA PAug 10, 2026

      Mood and energy also sleep

      Leslie KJul 15, 2026

      Boost my mood

      MARY MJun 4, 2026
      Where is it actually made, and from where are the actual ingredients?
      Ronald ONov 26, 2014

      Best Answer:  The Vitamin Shoppe should be able to provide the answers to your questions, Ronald. After all, it is their products that we are buying, right? I used this product at bedtime to give me a better quality of sleep. It appears to be effective.

      Good luck.

      Lillie BNov 26, 2014
      Reply
      Inaccurate
      Answer by Lillie B has been flagged
      Has anyone used this while on statins?
      A shopperDec 6, 2013

        I take this with a beta blocker with no issues. A store associate checked for interactions for me before I purchased. I would call customer service and ask them to check for you if you haven't already. Works great for me, I take it for anxiety / positive mood.

      Rebecca SDec 7, 2013
      Reply
      Inaccurate
      Answer by Rebecca S has been flagged

        Yes; no problems.

      Robert PDec 7, 2013
      Reply
      Inaccurate
      Answer by Robert P has been flagged

      Vote for the best answer above!

      Questions for Similar Products
      What is this used for?
      5-HTP With Vitamin B6
      About
      5-HTP With Vitamin B6
      A shopperNov 26, 2014

        It helps to regulate and support moods. The lows are not as low and the highs still feel great. It can control appetite because it regulates your moods. NOT like a narcotic! Definitely recommend. It is the one supplement I do not skip.

      Suzanne FNov 26, 2014
      Reply
      Inaccurate
      Answer by Suzanne F has been flagged

        5-HTP is a serotonin precursor. It is naturally occurring in the body but with age diminishes in quantity. It helps with low grade depression, sleep and energy, in my personal experience.

      Peter KNov 26, 2014
      Reply
      Inaccurate
      Answer by Peter K has been flagged

      Vote for the best answer above!

      How/when do you take this for insomnia? Does it affect your weight?
      5-HTP With Vitamin B6
      About
      5-HTP With Vitamin B6
      RhondaFeb 9, 2013

        I take it at night before bed (try one hour before or right at bedtime and then whatever works stick with the same time taking it and going to bed each night to get in a routine). No it does not normally affect weight. If you struggle with weight gain, and have low serotonin levels, it should help you lose it over time by establishing proper serotonin levels-and getting proper rest of course will help too.

      I hope it works for you as it does me!!

      Andrea JFeb 11, 2013
      Reply
      Inaccurate
      Answer by Andrea J has been flagged

        Take it about an hour before sleep
      If you sleep well this can increase your
      natural human growth hormone which improves your metabolism and could lead to some weight lass If that is what you need.

      Carole DFeb 11, 2013
      Reply
      Inaccurate
      Answer by Carole D has been flagged

        I don't take it for insomnia, but I do take one in the am. It does not affect my weight i.e. weight gain. If it did, I wold not be happy.

      Patricia JFeb 19, 2013
      Reply
      Inaccurate
      Answer by Patricia J has been flagged

        I take 5-HTP about one hour before bedtime. It has not affected my weight. No problems at all!

      Denise KFeb 19, 2013
      Reply
      Inaccurate
      Answer by Denise K has been flagged

        Both for mood. No notable weight effect. Will get more when I can afford it.

      Mary MFeb 11, 2013
      Reply
      Inaccurate
      Answer by Mary M has been flagged

      Vote for the best answer above!

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      BrandThe Vitamin Shoppe
      Health ConcernsMood Support
      HomeHerbs & Natural RemediesShop By ConcernSleep & Mood5-HTP with Vitamin B6 for Mood Support - 100 MG (120 Capsules)

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