First, why do you want to take methyl folate, 5000 mcg?
My Doc who is an ARNP prescribed it for the severe spasms and cramps in my legs. I tried the low-dose form available without a prescription, but did not have any results. I bought the quite expensive 5-MTHF he had prescribed and worked up to taking 10 mg every morning and it has helped somewhat. Unfortunately the high dose is not available at Vitamin Shoppe. The brand is Thorne Research in Idaho. It is -- for sixty 5 mg capsules. A bottle lasts a month at 10 mg a day.
Good luck!

  I have been taking Jarrow Formula Methyl B-12 5000 Mcg, Metoprolol and Lipitor daily for several years. I have had no problems. I think Jarrow is a good brand. I have been buying it from Vitamin Shoppe. Of course, I am not a medical professional. If you are concernd, you should ask your doctor.

  You need to check with a qualified holistic health practitioner. I don't know about interactions with drugs. Methyl B-12 is was a good product for me, yet might not be for you.

  Not a doctor but I don't see any problem taking this vitamin B. My father takes many more bp meds and others and he takes this vitamin B and is fine.

  I have high blood pressure treated with medication, and I have no problem taking Methyl B-12 5000mg.

  It's a lozenge -- place on your tongue and let it dissolve. The theory is that the B12 can be absorbed through the blood vessels of the tongue and jaw without being destroyed by stomach enzymes and acidity if it were to be swallowed.

  It is a chewable and my doctor did not specify anything about how I took it. My doctor is a homeopathic MD. You might check with one in your area if you are unsure.

  Nope. I have taken it all different times of the day and never had any issues.

  You let them melt under your tongue. No food or water needed.

  Yes it is fine to cut these in half.... They are to be melted in the mouth..there is no time release or capsule.

  Yes. I cut them in quarters

  I take this to help correct a genetic defect with MTHFR and B12 recycling. It is my understanding that methyl folate and methyl B12 are best absorbed first in the morning on an empty stomach away from other supplements. That is when I take mine.

  I take it first thing in morning, before food, to deal with possible homocysteine build-up with interrupted sleep, and before stomach acids start responding to food.