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Neprinol AFD Advanced Fibrin Defense - 500 MG (300 Capsules)

Neprinol AFD Advanced Fibrin Defense - 500 MG (300 Capsules)

$149.99
($0.49/serving)

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Neprinol AFD Advanced Fibrin Defense - 500 MG (300 Capsules)

Rated 4.6 out of 5
7 Reviews|6 Questions | 140 Answers|
  • Neprinol 300 capsules bottle front
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    Main Product
      Gluten FreeLactose FreeKosherSugar FreeVegetarianVegan
      GET ADVICE FROM A HEALTH ENTHUSIAST
      $149.99
      ($0.49/serving)

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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
      ×
      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      Arthur Andrew Medical
      Neprinol AFD Advanced Fibrin Defense - 500 MG (300 Capsules)
      Or

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      Product Info

      About This Product

      Advanced Fibrin Defense

      *Neprinol Supports:

      • Normal Inflammatory Response*
      • Normal Immune Function*
      • Enhanced Blood Cleansing*
      • Normal Blood Viscosity*
      • Optimal Circulatory Health*
      • Healthy CrP & Fibrin Levels*

      Neprinol is a proprietary combination of nattokinase serrapeptase, rutin, amla and other proteolytic enzymes specifically formulated to assist and defend your body from the damaging effects of fibrin. As fibrin builds up in our bodies, it may cause many unhealthy conditions. *Neprinol can help fibrin and its harmful effects under control. Neprinol can be used with other dietary supplements.

      **These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.

      Read More

      Directions

      Take 1 to 4 capsules with 8 oz of water between meals or as directed by your health physician.

      Warning

      Do not take this product without the consent of your physician if you are currently taking anti-coagulants or if you are pregnant or lactating. Keep out of reach of children. Store in a cool, dry place with lid tightly closed.

      Updated Jan 15, 2026
      Read More

      Supplement Facts

      Serving Size: 1 Capsule
      Number of Servings: 300 Servings
      Amount Per Serving
      % Daily Value
      MAGNESIUM  - (As Citrate)
      8 MG
      2%
      PROPRIETARY BLEND NEPRINOL AFD   
      0 
      N/A*
      SYSTEMIC AND LIPOLYTIC  - (ENZYME BLEND: SERRAPEPTASE, NATTOKINASE, LIPASE)
      15,000 FU
      N/A*
      NEPRINOL PROTEASE BLEND:  - (PROTEASE (DERIVED FROM SERRATIA, B.SUBTILIS AND A.ORYZAE)
      0 
      N/A*
      NEPRINOL ENZYME AND COFACTOR BLEND  - (AMLA, PAPAIN, BROMELAIN, RUTIN, COENZYME Q 10)
      0 
      N/A*

      Other Ingredients:

      Cellulose (capsules).

      Does Not Contain:

      Preservative Free, Free of Artificial Sweeteners, Free of Artificial Flavors, Free of Artificial Colors, Free of Animal Derivatives

      How Do You Read A Supplement Facts Label?

      Specifications

      Brand:
      Arthur Andrew Medical
      Form:
      Capsules
      Strength:
      500 MG
      Serving Size:
      1 Capsule
      Number of Servings:
      300 Servings
      Price per Serving:
      ($0.50 / serving)
      Product Weight:
      9  OZ
      Allergens:
      Milk Free, Egg Free, Peanut Free, Tree Nut Free, Fish Free, Shellfish Free, Soy Free, Wheat Free
      Specialty Diets:
      Gluten Free ,  Lactose Free ,  Kosher ,  Kosher Pareve ,  Sugar Free ,  Unsweetened ,  Vegetarian ,  Vegan ,  Low Carb ,  Paleo Friendly ,  Corn Free ,  Dairy Free ,  Salt Free ,  Starch Free ,  Yeast Free
      Item # :
      A7-1002 / 1679695

      Product Reviews
         (7)

      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      7 Ratings
      4.6out of 5 stars
      7 Ratings

      Rated 5 stars by 71% of reviewers

      571%

      Rated 4 stars by 14% of reviewers

      414%

      Rated 3 stars by 14% of reviewers

      314%

      Rated 2 stars by 0% of reviewers

      20%

      Rated 1 star by 0% of reviewers

      10%
      7 Reviews
      • checkMost Recent
      • Most Helpful
      • Oldest
      • Highest Rated
      • Lowest Rated
      • (5)
      • (1)
      • (1)
      • (0)
      • (0)
      • Under 18 (0)
      • 18-24 (0)
      • 25-34 (0)
      • 35-44 (0)
      • 45-54 (1)
      • 55-64 (0)
      • 65+ (1)
      May 20, 2025
      Rated 5 out of 5
      Amazing Results
      After using this supplement for a full seven days now, I feel my joint pain disappearing and I am waking up more refreshed. I am in my 50's and over the weekend I chopped and hauled wood so my expectation was that the next morning my body would be sore as it usually is, but this time the soreness was minimal. Adding this to auto reorder now.

      On the product's website it mentions this outcome will be around the 30 day mark, but my body is hypersensitive to most meds to it's natural to assume the same with supplements, so YMMV.
      Clark S
      Location
      Dallas, TX, US
      Gender
      Male
      Age Range
      45-54
      Would you recommend?:Yes
      Was this helpful?
      Review by Clark S has been flagged
      Flag
      Sep 18, 2020
      Rated 5 out of 5
      Neprinol review
      Easy to swallow. It seems to a little with my respiratory issue.
      LuAnnVerified Purchaser
      Location
      Glendale, WI, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Aug 10, 2020
      Was this helpful?
      Review by LuAnn has been flagged
      Flag
      Feb 27, 2019
      Rated 5 out of 5
      good
      vey good
      Sam QVerified Purchaser
      Purchased on Feb 12, 2019
      Was this helpful?
      Review by Sam Q has been flagged
      Flag
      Feb 18, 2019
      Rated 4 out of 5
      Good Product
      Good Product
      TestProd T
      Location
      US
      Would you recommend?:No
      Was this helpful?
      Review by TestProd T has been flagged
      Flag
      May 22, 2018
      Rated 5 out of 5
      Effective product
      Helps with my nose congestion a lot.
      Zhancheng ZVerified Purchaser
      Location
      US
      Would you recommend?:Yes
      Purchased on May 7, 2018
      Was this helpful?
      Review by Zhancheng Z has been flagged
      Flag
      Nov 23, 2012
      Rated 3 out of 5
      RustyJames
      Enzymes twice a day
      RustyJames
      Location
      Scottsdale, Az
      Was this helpful?
      Review by RustyJames has been flagged
      Flag
      Mar 31, 2011
      Rated 5 out of 5
      So strong
      This is the strongest product I have ever taken hands down. I don't get nearly as soar after the gym anymore. I would recommend this product to anyone.
      A Vitamin Shoppe Customer
      Location
      Undisclosed
      Was this helpful?
      Review by A Vitamin Shoppe Customer has been flagged
      Flag
      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      6 Questions
      Most Recent Question
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      Most Recent Answer
      Oldest Answer
      Why did you choose this?
      The Vitamin ShoppeStore

      Helps with my arthritic fingers. Game changer for me.

      Helen KAug 8, 2026

      Great for joints

      TETYANA AApr 24, 2026

      Great product

      MICHAEL FFeb 22, 2026

      Because I really enjoy this item

      Christopher BOct 12, 2025
      I want to know whether this item would be helpful for patients who suffered from intracranial hemorrhage and hemiplegia in the right side of body for the impression of the motor cortex in the brain. Will it help the patients to recover from the hemiplegia?
      Honghong T.Sep 26, 2015

        I am not a doctor. I primarily take Neprinol for muscle aches when I go to the gym, for reducing inflammation, for cleaning up excess fibrin form scar tissue, and keeping veins and arteries clear, but I would NOT NOT NOT take Neprinol for any kind of bleeding disorder. It is my understanding that it can thin the blood over time. Please consult with a physician before taking this for the problem you have described in your question.

      Lindy CSep 27, 2015purchased Apr 22, 2014
      Reply
      Inaccurate
      Answer by Lindy C has been flagged

        I am sure that it will help patient recover from hemiplegia by strengthening blood vessels, reduce inflammation and return blood viscosity to normal .

      Been-LingSep 30, 2015purchased Jun 28, 2015
      Reply
      Inaccurate
      Answer by Been-Ling has been flagged

        I do not Know. I take it to protect against blood clots. All the drugs are dangerous.

      Bryant GSep 26, 2015purchased May 6, 2014
      Reply
      Inaccurate
      Answer by Bryant G has been flagged

        I'm so sorry but I would not know the answer to your question.

      Debby LSep 26, 2015purchased Jul 11, 2014
      Reply
      Inaccurate
      Answer by Debby L has been flagged

        I do not know. I use it for digestive issues

      jorge cSep 27, 2015purchased Jan 9, 2014
      Reply
      Inaccurate
      Answer by jorge c has been flagged

      Vote for the best answer above!

      Does this product help if you have fibroids?
      ALAN B.Jul 24, 2022

        I have no idea about fibroids - I take it for my joints.

      JerryJul 25, 2022purchased Nov 9, 2019
      Reply
      Inaccurate
      Answer by Jerry has been flagged

        Absolutely yes

      randal LJul 24, 2022purchased Nov 18, 2019
      Reply
      Inaccurate
      Answer by randal L has been flagged

        Yes!

      James MJul 24, 2022purchased May 17, 2020
      Reply
      Inaccurate
      Answer by James M has been flagged

      Vote for the best answer above!

      Will Neprinol help clean arteries?
      A shopperFeb 1, 2015

        Neprinol helps break up fibrin in arteries which causes clots and clogged veins. Nattokinase does the same thing for a lot less $.

      Donna SFeb 1, 2015
      Reply
      Inaccurate
      Answer by Donna S has been flagged

        The information I have is that it will.

      Bryant GSep 26, 2015purchased May 6, 2014
      Reply
      Inaccurate
      Answer by Bryant G has been flagged

      Vote for the best answer above!

      I would like to know if anyone with sarcoid of the lungs has bennifitted from takin this product,and if so, what was your dosage start, finish, or maintenance? Thanks Chuck
      charles tNov 24, 2014

      Best Answer:  I'm sorry but I do not have an answer relative to this condition.

      Mark CNov 24, 2014
      Reply
      Inaccurate
      Answer by Mark C has been flagged
      How long does it take to stabilize the dosage required to maintain constant PTT levels?
      bill m.Feb 21, 2014

      Best Answer:  It may take two or three weeks. You will also need to slowly increase the dosage as you may have a reaction initially, which is your intestines and body adjusting to the digestive aids.

      Thomas CFeb 21, 2014
      Reply
      Inaccurate
      Answer by Thomas C has been flagged
      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      Shipping Info

       

      FREE STANDARD SHIPPING on orders of $45 or more

      How to get FREE Standard Shipping:

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      2. Place your online order of $45 or more* - after promotions and before tax are applied
      3. Use "Standard" shipping option at checkout

      Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

       

      *Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

       

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      back to top

      Experts Break it Down


      The Importance Of Supporting Your Joints—At Any Age

      The Importance Of Supporting Your Joints—At Any Age

      The importance of healthy joints isn’t emphasized as much as healthy muscles—but it should be. Don’t wait until your joints start yelling at you to give them some attention; support your joints now with these tips so you can move and perform well for years to come.

      7 Research-Backed Ways To Protect Your Joints

      7 Research-Backed Ways To Protect Your Joints

      Typically, joint issues start wreaking havoc around the age of 50—and things definitely won’t improve if you ignore the issue.

      6 Supplements I Take To Grease My Achy Joints

      6 Supplements I Take To Grease My Achy Joints

      Waking up feeling like the Tin Man—back so stiff I can’t bend over to touch my toes and knees so achy they feel glued in place—has been my reality for nearly five years.

      br_related_rid : R1vfuesukc09qadu3gnd0-r1,m0,uf
      br_iuid : aHR0cHM6Ly93d3cudml0YW1pbnNob3BwZS5jb20vcC9hcnRodXItYW5kcmV3LW1lZGljYWwtbmVwcmlub2wtNTAwLW1nLTMwMC1jYXBzdWxlcy9hNy0xMDAy
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      BrandArthur Andrew Medical
      Health ConcernsHealthy Joints
      HomeVitamins & SupplementsShop by ConcernJoint SupportNeprinol AFD Advanced Fibrin Defense - 500 MG (300 Capsules)
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      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.