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Glucosamine, Chondroitin, & MSM - Joint Support, Mobility, & Flexibility (240 Capsules)

Glucosamine, Chondroitin, & MSM - Joint Support, Mobility, & Flexibility (240 Capsules)

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Glucosamine, Chondroitin, & MSM - Joint Support, Mobility, & Flexibility (240 Capsules)

Rated 4.6 out of 5
17 Reviews|5 Questions | 352 Answers|
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Gluten FreeDairy FreeSoy FreeTree Nut Free

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About This Product

  • Supports joint health
  • Promotes mobility and flexibility
  • Free of gluten, dairy, soy, and nuts

From squats to human-or-fur-child-wrangling, cardio classes to dance-infused dishwashing, our joints know how to help us move through the day. That's why it's so important they get the support they need to keep supporting you.

Formulated specifically for your joints, The Vitamin Shoppe® brand Glucosamine, Chondroitin, & MSM capsules are perfect for promoting your mobility and flexibility.

Frequently Asked Questions

What is MSM?

Methylsulfonylmethane (MSM) is an organic compound known for its ability to support joint health by promoting flexibility and circulation while reducing occasional stiffness. Fun fact: it's the third largest nutrient found in the human body!

Read More

Directions

Take two (2) capsules three (3) times daily, preferably with meals.

Warning

Do not use this product if you are pregnant, nursing, allergic to shellfish or sulfur. Consult your healthcare provider prior to use if you are taking any medication, especially anticoagulants, or if you have any medical conditions, especially diabetes. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

Updated Jan 15, 2026
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Serving Size: 2 Capsules
Number of Servings: 120 Servings
Amount Per Serving
% Daily Value
GLUCOSAMINE SULFATE  - (AS GLUCOSAMINE SULFATE 2KCL)
**%
OPTIMSM  - (AS METHYLSULFONYLMETHANE)
**%
CHONDROITIN SULFATE  - (AS CHONDROITIN SULFATE SODIUM)(BOVINE)
**%

Other Ingredients:

Rice flour, gelatin (capsule), magnesium stearate, silicon dioxide.

Brand:
the Vitamin Shoppe
Form:
Capsules
Flavor:
Unflavored
Serving Size:
2 Capsules
Number of Servings:
120 Servings
Price per Serving:
($0.37 / serving)
Product Weight:
12  OZ
Allergens:
Soy Free, Tree Nut Free
Specialty Diets:
Gluten Free ,  Dairy Free
Item # :
VS-1656 / 1305673
17 Ratings
4.6out of 5 stars
17 Ratings

Rated 5 stars by 82% of reviewers

Rated 4 stars by 0% of reviewers

Rated 3 stars by 12% of reviewers

Rated 2 stars by 6% of reviewers

Rated 1 star by 0% of reviewers

Would you recommend?
1-10 of 17 Reviews
Rated 2 out of 5
Sep 11, 2025
Too many empty and or spilled capsules and haven't noticed improvement
I'm not impressed with this product. Several capsules were empty and or spilled out onto the other capsules and I haven't noticed any improvement in my joints yet. Not sure I'll be buying this one again.T
John P
Rated 5 out of 5
Nov 10, 2021
Love itHey
They are easy to take and I have found them to be very effective and when I forget one day I can feel it.
BARBARA S
Rated 3 out of 5
May 11, 2021
Vit
I use this 2 x daily
Tracey
Rated 5 out of 5
Apr 30, 2021
Free of junk fillers and effective
It doesn't have the sodium many products have. It works. This It not my 1st purchase.
TOM S
Rated 5 out of 5
Feb 21, 2021
It Works!
I started taking this supplement after I noticed a cracking sound in my knees and hips. My doctor said it was arthritis. I noticed a difference in one week after taking this supplement. The cracking sounds went away and my joints feel better. I notice a difference when I stop taking it after running out. The joint discomfort returns and slowly the crack sounds follow.
Alicia B
Rated 5 out of 5
Aug 9, 2020
Glucosamine Chondroitin MSM
Used this brand for years. Seems to be working for me.
Terry M
Rated 3 out of 5
Jul 15, 2020
Not sure yet
Not sure how well it works may try one more bottle to see if I just need more time with it .
Cody R
Rated 5 out of 5
Aug 11, 2018
the best brand on the market
well i have using this product for about 3 months but a different brand , but when trying to buy it again i read about the product , and it was said that the vitamin shoppe had the best product on the market so this is why i brought this brand
King B
Rated 5 out of 5
Mar 15, 2017
I would like to buy it again
Working good.
Emin
Rated 5 out of 5
Dec 31, 2014
Pain is gone.
I use this for a L4-L5 bulging and dehisced disc. Before using GC w/ MSM, I had pain getting in and out of the car... and pretty much with every movement. After taking GC w/ MSM I started noticing I had no pain and felt "normal." I still can't do the things I know I shouldn't do (twisting exercise, vacuum, things that people a bulging disc can't do) but I am pain free with GC w/ MSM outside of those things.

If I don't take the GC w/ MSM or if I run out- by day 3 or so, I feel it. You definitely have to take it EVERY day.

I am allergic to sulfa, but I have no problems taking these. Sulfa and sulfur must be different? I have no side effects at all.
Stephanie
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

We'll email them your question, then email you their replies.

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5 Questions
Why did you choose this?
The Vitamin ShoppeStore

Great product. Not many include MSM. It’s the trifecta!

Jimmy K

flexibility and price

Dmitry G

for joints

Edgar M

Has helped my joint pain especially in my hips!

Susan B
Can i take these pills if im 15 years old?
Aaron B

Best Answer:  I am not a doctor or healthcare practitioner of any kind. I am 80 and my wife is 77. We both take Glusoamine & Chondroitin with MSM every day. If we don't, within 3-4 days our joints begin to ache and get sore. With these 3 items, we reduce inflammation (soreness, aching) of the joints to almost zero. Usually, young people do not need this if on a good diet. Should you see your doctor? A nurse? Your pharmacist? You might have a problem that this will not respond to. 30 days is a good period to try this product if you have joint problems.

Dan C
Is this product safe for dogs? My dog is 90-95lbs and vet recommended a number of dog brands but the ingredients seem similar (not exact) to this product that I take daily. Anyone have advice on using this on dogs?
A shopper

Best Answer:  This is formulated for human use only and not formulated to be used by dogs.

Daniel W.staff
Is it made in USA?
Steve
Where is it made?
A shopper
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

 

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Experts Break it Down

The Importance Of Supporting Your Joints—At Any Age

The Importance Of Supporting Your Joints—At Any Age

The importance of healthy joints isn’t emphasized as much as healthy muscles—but it should be. Don’t wait until your joints start yelling at you to give them some attention; support your joints now with these tips so you can move and perform well for years to come.

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    Frequently Asked Questions

    What is MSM?

    Methylsulfonylmethane (MSM) is an organic compound known for its ability to support joint health by promoting flexibility and circulation while reducing occasional stiffness. Fun fact: it's the third largest nutrient found in the human body!

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