SAM-e - Enteric Coated - Mood, Joint, & Liver Support - 400 MG (30 Tablets)

SAM-e - Enteric Coated - Mood, Joint, & Liver Support - 400 MG (30 Tablets)

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About This Product

  • Provides mood support
  • Supports joint and liver health
  • Free of gluten, dairy, soy, and nuts

The Vitamin Shoppe® brand SAM-e tablets are perfect for when your mood needs a little support. S-adenosylmethionine (SAM-e) is a compound involved in the production of serotonin and dopamine—AKA our feel-good hormones. Studies show that SAM-e can also promote joint and liver health.

Add this supplement to your routine to support a positive mood, flexible joints, and a healthy liver.

Frequently Asked Questions

What is an enteric coating?

An enteric coating protects the supplement from the harsh, acidic environment of the stomach. It allows the supplement to release once it passes through the stomach for optimal absorption.

Directions

Take one (1) tablet per day on an empty stomach, or as directed by your physician.

Warning

Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

Read More
Serving Size: 1 Tablet
Number of Servings: 30 Servings
Amount Per Serving
% Daily Value
S-ADENOSYL-L-METHIONINE  - (SAM-E) (AS S-ADENOSYL-L-METHIONINE TOSYLATE DISULFATE)
N/A*

Other Ingredients:

Cellulose, silica, magnesium stearate, riboflavin, ethyl cellulose, oleic acid, medium chain triglycerides, sodium alginate, modified cellulose, triacetin, calcium carbonate, ammonium hydroxide.

Brand:
the Vitamin Shoppe
Form:
Tablet(s)
Strength:
400 MG
Serving Size:
1 Tablet
Number of Servings:
30 Servings
Price per Serving:
($0.53 / serving)
Product Weight:
5  OZ
Allergens:
Soy Free ,  Tree Nut Free
Specialty Diets:
Gluten Free ,  Dairy Free
Item # :
VS-2293 / 1563865
15 Ratings
3.7out of 5 stars
15 Ratings

Rated 5 stars by 53% of reviewers

Rated 4 stars by 20% of reviewers

Rated 3 stars by 0% of reviewers

Rated 2 stars by 0% of reviewers

Rated 1 star by 27% of reviewers

Would you recommend?
1-10 of 15 Reviews
Rated 1 out of 5
Mar 15, 2025
Meh
Tried it, didn't feel a difference in my mood. Finished entire bottle, will try something else.
Rated 5 out of 5
Mar 6, 2023
SAM-e
Good product at a reasonable price. I would recommend the SAM-e to anybody who uses it, the vitamin shoppe product is of quality.
Rated 1 out of 5
Feb 22, 2023
ammonia hydroxide, attention!
how can they put ammonia hydroxide in the supplement, read the other ingredients! crazy, this ingredient alone is very toxic
Rated 5 out of 5
Sep 15, 2021
Great
Great product
Rated 4 out of 5
Aug 17, 2021
Good product for mood support
I took the Vitamin Shoppe's version of SamE and noticed an improvement in my mood - I suffer from moderate anxiety and I'm always looking for natural alternatives to prescription meds. Work and everyday stress wasn't as intense, so this product worked well for me. One thing I noticed, which is probably rare for most people, is that I developed acne a few days after taking it. I've been taking SamE daily for the past two weeks and I have new breakouts everyday that haven't cleared up. I'm 35 and my skin has been clear for years, so this was no coincidence.
Rated 1 out of 5
Jul 10, 2021
Not digestible
The Enteric coating went Enterically through me. Literally throwing money into the toilet.
Rated 5 out of 5
Mar 10, 2021
We don’t buy any other brand!
Great quality product
Rated 4 out of 5
Jan 3, 2021
Mood eveners
I take this to help even out my moods. These aren’t happy pills but give me less down days.
Rated 5 out of 5
Dec 15, 2020
Same good for winter blahs
Excellent product!
Rated 4 out of 5
Dec 3, 2020
BJ
Like SAM-e product from Vitamin Shoppe. Wish it was always in dtock and available for shipping.
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.

We'll email them your question, then email you their replies.

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5 Questions
Why did you choose this?

Joint health

good for liver

Used before.

Controls thumb joint pain

When is the best time to take. AM or PM ? With Food or empty stomach ?

Best Answer:  I believe the directions say that ist should be on an empty stomach with an hour before eating. I have found this is easier if I take it at bedtime which you should have an empty stomach and then first thing in the morning an hour before breakfast.
I am actually taking a different SAMe now but the procedure is the same.

What are the side effects experienced with this medicine?

Best Answer:  My husband has taken this for years for his RA. He experiences no side effects, feels it helps his RA and has the side benefit of being a mood stabilizer. Biggest drawback, it's expensive.

is this the butanedisulfonate form of Sam-e?
Does it help with RA joint pain? Removal of uric acid in hands and feet
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.

 

FREE STANDARD SHIPPING on orders of $35 or more

How to get FREE Standard Shipping:

  1. Ship to an address within the United States (including U.S. territories)
  2. Place your online order of $35 or more* - after promotions and before tax are applied
  3. Use "Standard" shipping option at checkout

Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

 

*Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

 

Orders for states outside of the continental U.S. (including those of $35 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

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