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Advanced Joint Support with UC-II Collagen (30 Capsules)

Advanced Joint Support with UC-II Collagen (30 Capsules)

$66.99
($2.23/serving)

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Advanced Joint Support with UC-II Collagen (30 Capsules)

Rated 4.3 out of 5
14 Reviews|4 Questions | 109 Answers|
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      $66.99
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      Instaflex
      Advanced Joint Support with UC-II Collagen (30 Capsules)
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      Slide 1 of 3

      Product Info

      About This Product

      Instaflex® Advanced featuring UC-II

      Just one small capsule once a day can lead to more comfortable joints in as little as 7 days.

      CLINICAL STUDIES SHOW:

      • Aprèsex® improves joint stiffness and discomfort by more than 60% when compared to placebo after 90 days.
      • UC-II® Collagen significantly reduces knee discomfort and is twice as effective as glucosamine plus chondroitin.
      • BioPerine® significantly enhances the bioavailability of nutrients through increased absorption.

      • Relieves Discomfort
      • Improve Flexibility
      • Joint Relief in 7 days.

      Read More

      Directions

      As a dietary supplement take one (1) capsule a day with water.

      Warning

      Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition or use any medications. For adult use only. Keep out of the reach of children.

      Updated Jan 15, 2026
      Read More

      Supplement Facts

      Serving Size: 1 Capsule
      Number of Servings: 30 Servings
      Amount Per Serving
      % Daily Value
      TURMERIC  - (RHIZOME)(STANDARDIZED TO MIN 95% CURCUMINOIDS
      200 MG
      N/A*
      RESVERATROL  - (FROM POLYGONUM CUSPIDATUM ROOT EXTRACT)
      100 MG
      N/A*
      APRESFLEX(R)  - (BOSWELLIA SERRATA EXTRACT)(RESIN)
      100 MG
      N/A*
      UC-II  - (10 MG TOTAL COLLAGEN, 3 MG UNDENATURED TYPE II COLLAGEN)
      40 MG
      N/A*
      HYALURONIC ACID  - (MIN 89%)
      5 MG
      N/A*
      BIOPERINE-BLACK PEPPER EXTRACT  - (FRUIT)(STANDARDIZED TO MIN 95% PIPERINE)
      5 MG
      N/A*

      Other Ingredients:

      Gelatin, cellulose, magnesium stearate, titanium dioxide and FD&C Blue #1.

      How Do You Read A Supplement Facts Label?

      Specifications

      Brand:
      Instaflex
      Form:
      Capsules
      Serving Size:
      1 Capsule
      Number of Servings:
      30 Servings
      Price per Serving:
      ($2.23 / serving)
      Product Weight:
      3  OZ
      Item # :
      DG-1005 / 2088227

      Who Might Benefit From This Product

      • Active Adults: This product may benefit individuals who maintain an active lifestyle by offering joint support and aiding in maintaining flexibility and comfort during physical activities.
      • Graceful Agers: Perfect for those seeking to support joint health as they age. This supplement promotes more comfortable movement, allowing you to continue enjoying favorite activities with ease.
      • Regular Gym Goers: Ideal for those who frequently visit the gym and experience joint discomfort from repetitive workouts. The advanced formula supports joint flexibility and aids in post-exercise recovery.
      • Busy Individuals: For those with a fast-paced schedule who need convenient joint support, this one-capsule-per-day solution helps maintain joint comfort and mobility without disrupting daily routines.
      • Individuals with Dietary Restrictions: Suitable for those who have to be cautious about their diet. This supplement provides an easy way to support joint health without worrying about common allergens.

      Read More

      Product Reviews
         (14)

      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      14 Ratings
      4.3out of 5 stars
      14 Ratings

      Rated 5 stars by 71% of reviewers

      571%

      Rated 4 stars by 14% of reviewers

      414%

      Rated 3 stars by 0% of reviewers

      30%

      Rated 2 stars by 0% of reviewers

      20%

      Rated 1 star by 14% of reviewers

      114%
      Would you recommend?
      1-10 of 14 Reviews
      • checkMost Recent
      • Most Helpful
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      • (10)
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      • Under 18 (0)
      • 18-24 (0)
      • 25-34 (0)
      • 35-44 (1)
      • 45-54 (0)
      • 55-64 (1)
      • 65+ (5)
      Sep 4, 2026
      Rated 5 out of 5
      Instaflex Advanced is a Great Product!
      I purchased Instaflex Advanced for my mother who was having joint issues that were affecting her mobility and this product has helped her tremendously. She felt the difference within days and she is already on her second bottle. This is a great product that I highly recommend.
      undefined uVerified Purchaser
      Location
      Hartford, CT, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Aug 1, 2026
      Was this helpful?
      Review by undefined u has been flagged
      Flag
      Aug 5, 2025
      Rated 1 out of 5
      Did nothing for my arthritis pain
      So far I have been using for 2 weeks and I do not feel a difference in my pain threshold.
      Therese CVerified Purchaser
      Location
      BURBANK, IL, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:No
      Purchased on Jul 14, 2025
      Was this helpful?
      Review by Therese C has been flagged
      Flag
      Jun 18, 2022
      Rated 4 out of 5
      ??
      I really like this product. I started to take it and within a week I could tell the difference in the aches n stiffness in my leg. I do not take it as much as I would like because of the high price.
      Linda LVerified Purchaser
      Location
      Horn Lake, MS, US
      Purchased on May 19, 2022
      Was this helpful?
      Review by Linda L has been flagged
      Flag
      Feb 1, 2022
      Rated 1 out of 5
      Didn?t
      Didn?t work for me
      JEROME DVerified Purchaser
      Purchased on Dec 25, 2021
      Was this helpful?
      Review by JEROME D has been flagged
      Flag
      Jan 20, 2022
      Rated 5 out of 5
      Instaflex Advanced is Awesome!
      I recently transitioned into a position that requires standing and walking for 8+ hours a day! The first few weeks, I could just barely bend my knees to get into my car to drive home. After trying pain relieving patches and creams which were only temporary fixes, I decided to try Instaflex and now I?m hooked! I absolutely don?t know what I would have done if I hadn?t found Instaflex!
      KarenVerified Purchaser
      Location
      US
      Purchased on Dec 18, 2021
      Was this helpful?
      Review by Karen has been flagged
      Flag
      Dec 28, 2020
      Rated 5 out of 5
      Awesome Product
      Awesome Product. Primary reason for me to get it, it contains Collagen 2. Many collagens purchased only have 1 and 3 for skin, hair and etc. Collagen is needed by the body. Because of our lifestyle and food source changes most people are deficit1
      Greta EVerified Purchaser
      Location
      Winston Salem, NC, US
      Would you recommend?:Yes
      Purchased on Nov 17, 2020
      Was this helpful?
      Review by Greta E has been flagged
      Flag
      Jul 26, 2020
      Rated 5 out of 5
      great joint supplement
      It' really helped my mother's knees, but it's hard to obtain.
      Yolanda KVerified Purchaser
      Location
      Incline Village, NV, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Jun 17, 2020
      Was this helpful?
      Review by Yolanda K has been flagged
      Flag
      Jul 14, 2019
      Rated 4 out of 5
      Good supplement
      They are good but too expensive IMO.
      jonathan m.Verified Purchaser
      Location
      brooklyn, NY, US
      Gender
      Male
      Age Range
      35-44
      Would you recommend?:Yes
      Purchased on Apr 8, 2019
      Was this helpful?
      Review by jonathan m. has been flagged
      Flag
      Jun 26, 2019
      Rated 5 out of 5
      Satisfied customer
      I really like this product!!
      Jeanie MVerified Purchaser
      Location
      Fort Walton Beach , FL, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on May 26, 2019
      Was this helpful?
      Review by Jeanie M has been flagged
      Flag
      Mar 2, 2019
      Rated 5 out of 5
      Easy and fast!
      Ordered! Shipped! Received! Satisfied!
      Mary Lynn KVerified Purchaser
      Location
      Chandler, AZ, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Feb 15, 2019
      Was this helpful?
      Review by Mary Lynn K has been flagged
      Flag
      • 1
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      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      4 Questions
      Most Recent Question
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      Oldest Answer
      Why did you choose this?
      The Vitamin ShoppeStore

      it does not have glucosamine which may contribute to dementia

      Paula GAug 18, 2026

      I was given a sample and loved it

      Karla AMay 5, 2026

      It works

      chris lFeb 24, 2026

      it helps my knees

      Michele DFeb 11, 2026
      what kind of gelatin?
      undefined uMay 22, 2024

      Best Answer:  Thank you for your inquiry. Regrettably, these details are not listed on the item. We recommend contacting the manufacturer directly for these specifics since this is a third party item not manufactured by The Vitamin Shoppe. You can reach the manufacturer directly through the following link to their official website: https://www.instaflex.com/contact

      Daniel W.staffMay 30, 2024
      Reply
      Inaccurate
      Answer by Daniel W. has been flagged
      what kind of gelatin?
      TomNov 16, 2018
      Does this product help with back pain?
      Shanay BDec 23, 2025
      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      Shipping Info

       

      FREE STANDARD SHIPPING on orders of $45 or more

      How to get FREE Standard Shipping:

      1. Ship to an address within the United States (including U.S. territories)
      2. Place your online order of $45 or more* - after promotions and before tax are applied
      3. Use "Standard" shipping option at checkout

      Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

       

      *Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

       

      Orders for states outside of the continental U.S. (including those of $45 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

      back to top

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      Waking up feeling like the Tin Man—back so stiff I can’t bend over to touch my toes and knees so achy they feel glued in place—has been my reality for nearly five years.

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      Slide 1 of 3

      Instaflex Advanced is a revolutionary joint health formula used to promote comfort and help reduce joint stiffness. This dietary supplement features important healthy ingredients for natural joint support in an easy-to-take capsule form. Instaflex ingredients include Apreflex®, which may help reduce discomfort and strain related to joint stiffness, UC-II® Collagen to promote joint flexibility, and BioPerine®, which may help support your body’s ability to absorb specific nutrients. Instaflex offers you a convenient way to enjoy greater joint mobility and comfort in everyday activities with a 30-count bottle of supplements.


      Are you experience aching in your joints from overuse or exercise? These natural supplements, along with exercise and a healthy lifestyle and diet, not only support relief from stiffness, but can also help improve joint strength and flexibility. Instaflex joint support relies on natural compounds to slow deterioration of cartilage, reduce discomfort associated with stiffness, and improve joint mobility. It’s important to note that some supplements may interfere with other medications, so if you have a serious medical condition, are taking other medications, or are pregnant or breastfeeding, be sure to check with your doctor before taking any dietary supplements.


      BrandInstaflex
      Health ConcernsMobilityHealthy Joints
      HomeVitamins & SupplementsShop by ConcernJoint SupportAdvanced Joint Support with UC-II Collagen (30 Capsules)

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