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Multi-Enzyme Digestive Formula (300 Tablets)

Rated 3.8 out of 5
44 Reviews|6 Questions | 291 Answers|
The Vitamin Shoppe Multi-Enzyme Digestive Formula tablets front
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    Main Product
      Gluten FreeDairy FreeSoy FreeTree Nut Free
      GET ADVICE FROM A HEALTH ENTHUSIAST
      $39.99
      ($0.26/serving)

      AUTO-DELIVERY SAVE 20%

      • One Flavor
      • 300 Tablet(S)$39.99
      • 100 Tablet(S)$17.99
      • 600 Tablet(S)$56.99
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
      ×
      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      Multi-Enzyme Digestive Formula (300 Tablets)
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      Product Info

      About This Product

      • Promotes nutrient digestion
      • Suitable for everyday wellness seekers
      • Free of gluten, dairy, soy, nuts, and artificial colors or flavors

      The Vitamin Shoppe® brand Multi-Enzyme tablets boast a full-spectrum enzyme formula to promote nutrient digestion. Each tablet contains proteases to support protein digestion, amylases for carbohydrate digestion, and lipases for fat digestion.

      To ensure you're getting the most out of your food, take two tablets after every meal.

      Read More

      Directions

      Take two (2) tablets after each meal. Do not take on an empty stomach.

      Warning

      Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

      Updated Jan 15, 2026
      Read More

      Supplement Facts

      Serving Size: 2 Tablets
      Number of Servings: 150 Servings
      Amount Per Serving
      % Daily Value
      CALCIUM  - (AS DICALCIUM PHOSPHATE)
      200 MG
      15%
      PHOSPHORUS  - (AS DICALCIUM PHOSPHATE)
      156 MG
      12%
      PANCREATIN  - (4X USP)(PORCINE) PROVIDING: PROTEASE 100 USP UNITS/MG, AMYLASE 100 USP UNITS/MG LIPASE 8 USP UNITS/MG)
      100 MG
      N/A*
      BETAINE HCL   
      400 MG
      N/A*
      AMYLASE  - (ASPERGILLUS ORYZAE)(5,000 FCC UNITS/GM)
      1,000 SKB
      N/A*
      PROTEASE  - (ASPERGILLUS ORYZAE)(5,000 FCC UNITS/GM)
      1,000 HUT
      N/A*
      PEPSIN  - (FROM PORCINE)(1:3000)
      100 MG
      N/A*
      PAPAIN  - (FROM PAPAYA)(2000 USP UNITS/MG)
      1,000 MG
      N/A*
      OX BILE POWDER  - (FROM BOVINE)
      30 MG
      N/A*
      LIPASE  - (ASPERGILLUS NIGER)(5000 FCC UNITS/G)
      250 FIP
      N/A*
      BROMELAIN  - (FROM PINEAPPLE)(600 GDU/G)
      12 GDU
      N/A*
      CELLULASE  - (TRICHODERMA REESEI)(20,000 FCC UNITS/G)
      400 CU
      N/A*

      Other Ingredients:

      Microcrystalline cellulose, stearic acid, croscarmellose sodium, aqueous coating, magnesium stearate, silicon dioxide, natural peppermint flavor.

      Does Not Contain:

      Free of Artificial Flavors, Free of Artificial Colors

      How Do You Read A Supplement Facts Label?

      Specifications

      Brand:
      The Vitamin Shoppe
      Form:
      Tablet(s)
      Serving Size:
      2 Tablets
      Number of Servings:
      150 Servings
      Price per Serving:
      ($0.27 / serving)
      Product Weight:
      12  OZ
      Allergens:
      Soy Free, Tree Nut Free
      Specialty Diets:
      Gluten Free ,  Dairy Free
      Item # :
      VS-1195 / 1040236

      Product Reviews
         (44)

      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      44 Ratings
      3.8out of 5 stars
      44 Ratings

      Rated 5 stars by 64% of reviewers

      564%

      Rated 4 stars by 5% of reviewers

      45%

      Rated 3 stars by 5% of reviewers

      35%

      Rated 2 stars by 2% of reviewers

      22%

      Rated 1 star by 25% of reviewers

      125%
      Would you recommend?
      1-10 of 44 Reviews
      • checkMost Recent
      • Most Helpful
      • Oldest
      • Highest Rated
      • Lowest Rated
      • (28)
      • (2)
      • (2)
      • (1)
      • (11)
      • Under 18 (0)
      • 18-24 (0)
      • 25-34 (0)
      • 35-44 (0)
      • 45-54 (7)
      • 55-64 (4)
      • 65+ (5)
      Jan 8, 2026
      Rated 5 out of 5
      This is the best product for digestive issues
      I started taking this a couple of years after I had my gallbladder removed. The Naturopathic Doctor had suggested that I take a product that had lipase to help with the break down of fried foods and other foods.
      It took me a while to really appreciate this product and it is now part of my daily regimen. I have found this multi enzyme supplement to be very helpful in the most unexpected ways, like when I ate something that quite agree with my body.
      undefined uVerified Purchaser
      Purchased on Dec 23, 2025
      Was this helpful?
      Review by undefined u has been flagged
      Flag
      Oct 18, 2024
      Rated 1 out of 5
      Watch out if you are Celiac patient.
      Be careful Here! It says Gluten Free but when I took this product had multiple diarrhea episodes. Thought maybe it was bad food and tried again with same results. Then I read with magnifier , on bottle it lists Wheat under contents. I live 44.5 miles from nearest store and I was told I was outside the 30 day return policy. We have just had2 hurricanes in last month, you would think some help would be forthcoming.
      Karen W
      Location
      Crystal River, FL, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:No
      Was this helpful?
      Review by Karen W has been flagged
      Flag
      May 24, 2024
      Rated 2 out of 5
      Causes constipation
      Causes constipation.
      yolanda H
      Location
      Bristol, TN, US
      Gender
      Female
      Age Range
      45-54
      Would you recommend?:No
      Was this helpful?
      Review by yolanda H has been flagged
      Flag
      Oct 24, 2023
      Rated 5 out of 5
      Great multi enzyme
      Great way to assimilate all your nutrients and a must for Thanksgiving when you're over eat
      JORGE SVerified Purchaser
      Location
      Miami, FL, US
      Gender
      Male
      Age Range
      45-54
      Would you recommend?:Yes
      Purchased on Apr 3, 2014
      Was this helpful?
      Review by JORGE S has been flagged
      Flag
      Aug 4, 2022
      Rated 5 out of 5
      Great Purchase!!!
      This is likely the best thing that?s happened to me!! In just a few days of using supplement, I?ve gone from 1-2 BM a week to 1-2 a day!! The size of the pill is no problem, swallows easily. Also, I like the hint of mint flavor I taste when I pop them in my mouth.
      Location
      Springfield, IL, US
      Gender
      Female
      Age Range
      45-54
      Would you recommend?:Yes
      Was this helpful?
      Review by has been flagged
      Flag
      Mar 2, 2022
      Rated 1 out of 5
      NO!
      These did not work for me. The digestive enzymes were unavailable, so I ordered these as a substitute. There was a significant increase in digestive issues experienced while taking. No relief was provided by these
      lakecha f
      Would you recommend?:No
      Was this helpful?
      Review by lakecha f has been flagged
      Flag
      Nov 17, 2021
      Rated 5 out of 5
      Best Enzymes
      I have tried others but have always came back to the vitamin shoppe brand, they work better and are not expensive.
      Lori P.Verified Purchaser
      Location
      Georgetown, FL, US
      Gender
      Female
      Age Range
      55-64
      Would you recommend?:Yes
      Purchased on Sep 15, 2021
      Was this helpful?
      Review by Lori P. has been flagged
      Flag
      Sep 21, 2021
      Rated 1 out of 5
      This is a hard pill to swallow!
      Seriously, hard to get these down and you're supposed to take 2 per serving. They should change the shape and make them oval so they're narrower.
      Karen RVerified Purchaser
      Location
      Mayfield Hts, OH, US
      Gender
      Female
      Age Range
      55-64
      Would you recommend?:No
      Purchased on Aug 22, 2021
      Was this helpful?
      Review by Karen R has been flagged
      Flag
      Apr 27, 2021
      Rated 5 out of 5
      Awesome product
      Awesome great for right after you eat your meals breakdown all food
      Carlos RVerified Purchaser
      Location
      Kissimmee, FL, US
      Gender
      Male
      Age Range
      45-54
      Would you recommend?:Yes
      Purchased on Apr 24, 2021
      Was this helpful?
      Review by Carlos R has been flagged
      Flag
      Apr 11, 2021
      Rated 5 out of 5
      They work
      They really do work to help your food digest!
      kathy gVerified Purchaser
      Location
      Salinas, CA, US
      Gender
      Female
      Age Range
      55-64
      Would you recommend?:Yes
      Purchased on Mar 3, 2021
      Was this helpful?
      Review by kathy g has been flagged
      Flag
      • 1
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      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      6 Questions
      Most Recent Question
      Oldest Question
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      Fewest Answers
      Most Recent Answer
      Oldest Answer
      Why did you choose this?
      The Vitamin ShoppeStore

      I have used this product for years and have always been pleased with the results.

      MAGGIE GJul 25, 2026

      It works

      Vicki GJul 9, 2026

      I need it

      Tracey MJun 9, 2026

      It works

      Eric MMay 20, 2026
      Are the tablets supposed to be swallowed or chewed?
      A shopperJun 16, 2013

      Best Answer:  I tried chewing one and it was so unpalatable I'll never try again. It has a somewhat slick surface, which makes it easy to swallow. I believe the enzymes are to do their work in the stomach rather than in the mouth, so it wouldn't be important to chew them.

      Joan HJun 16, 2013
      Reply
      Inaccurate
      Answer by Joan H has been flagged
      how big is pill?
      A shopperAug 12, 2015

      Best Answer:  Slightly larger than a circular aspirin pill and about 1 1/2 as thick. It is worth taking because it works very well for digestion.

      pamela hAug 12, 2015purchased Sep 9, 2013
      Reply
      Inaccurate
      Answer by pamela h has been flagged
      should this be taken half way through the meal, or only at the end?
      Brad KSep 15, 2017

      Best Answer:  I always take mine at the start of a meal. I've read that it's most effective then.

      MARYSep 16, 2017purchased Sep 30, 2015
      Reply
      Inaccurate
      Answer by MARY has been flagged
      Is this coated for acid protection?
      Abhijit R.Dec 23, 2014

      Best Answer:  My observation is that they are uncoated. They seem to be a "pressed" amalgam of the ingredients, which can be used tasted if kept on the tongue more than a few seconds.

      neil bDec 23, 2014
      Reply
      Inaccurate
      Answer by neil b has been flagged
      Is acidophilus of the enzymes in this product?
      Bonni L.Aug 2, 2022

      Best Answer:  not that I am aware of

      PeggiAug 3, 2022purchased Jul 25, 2021
      Reply
      Inaccurate
      Answer by Peggi has been flagged
      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      Shipping Info

       

      FREE STANDARD SHIPPING on orders of $45 or more

      How to get FREE Standard Shipping:

      1. Ship to an address within the United States (including U.S. territories)
      2. Place your online order of $45 or more* - after promotions and before tax are applied
      3. Use "Standard" shipping option at checkout

      Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

       

      *Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

       

      Orders for states outside of the continental U.S. (including those of $45 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

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      HomeDigestion & Gut HealthEnzymesDigestive EnzymesMulti-Enzyme Digestive Formula (300 Tablets)

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      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
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      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.