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Multi-Enzyme Digestive Formula (600 Tablets)

Multi-Enzyme Digestive Formula (600 Tablets)

$56.99
($0.18/serving)

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Multi-Enzyme Digestive Formula (600 Tablets)

Rated 3.9 out of 5
117 Reviews|9 Questions | 212 Answers|
The Vitamin Shoppe Multi-Enzyme Digestive Formula bottle front
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    Main Product
      Gluten FreeDairy FreeSoy FreeTree Nut Free
      GET ADVICE FROM A HEALTH ENTHUSIAST
      $56.99
      ($0.18/serving)

      BOGO

      BUY ONE, GET ONE 50% OFF

      EXCLUDED FROM COUPONS
      • One Flavor
      • 600 Tablet(S)$56.99
      • 100 Tablet(S)$17.99
      • 300 Tablet(S)$39.99
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
      ×
      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      Multi-Enzyme Digestive Formula (600 Tablets)
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      Product Info

      About This Product

      • Promotes nutrient digestion
      • Suitable for everyday wellness seekers
      • Free of gluten, dairy, soy, nuts, and artificial colors or flavors

      The Vitamin Shoppe® brand Multi-Enzyme tablets boast a full-spectrum enzyme formula to promote nutrient digestion. Each tablet contains proteases to support protein digestion, amylases for carbohydrate digestion, and lipases for fat digestion.

      To ensure you're getting the most out of your food, take two tablets after every meal.

      Read More

      Directions

      Take two (2) tablets after each meal. Do not take on an empty stomach.

      Warning

      Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

      Updated Jan 15, 2026
      Read More

      Supplement Facts

      Serving Size: 2 Tablets
      Number of Servings: 300 Servings
      Amount Per Serving
      % Daily Value
      CALCIUM  - (AS DICALCIUM PHOSPHATE)
      200 MG
      15%
      PHOSPHORUS  - (AS DICALCIUM PHOSPHATE)
      156 MG
      12%
      PANCREATIN  - (4X USP)(PORCINE) PROVIDING: PROTEASE 100 USP UNITS/MG, AMYLASE 100 USP UNITS/MG LIPASE 8 USP UNITS/MG)
      100 MG
      N/A*
      BETAINE HCL   
      400 MG
      N/A*
      AMYLASE  - (ASPERGILLUS ORYZAE)(5,000 FCC UNITS/GM)
      1,000 SKB
      N/A*
      PROTEASE  - (ASPERGILLUS ORYZAE)(5,000 FCC UNITS/GM)
      1,000 HUT
      N/A*
      PEPSIN  - (FROM PORCINE)(1:3000)
      100 MG
      N/A*
      PAPAIN  - (FROM PAPAYA)(2000 USP UNITS/MG)
      200,000 EA
      FCCU%
      OX BILE POWDER  - (FROM BOVINE)
      30 MG
      N/A*
      LIPASE  - (ASPERGILLUS NIGER)(5000 FCC UNITS/G)
      250 FIP
      N/A*
      BROMELAIN  - (FROM PINEAPPLE)(600 GDU/G)
      12 GDU
      N/A*
      CELLULASE  - (TRICHODERMA REESEI)(20,000 FCC UNITS/G)
      400 CU
      N/A*

      Other Ingredients:

      Microcrystalline cellulose, stearic acid, croscarmellose sodium, aqueous coating, magnesium stearate, silicon dioxide, natural peppermint oil.

      Does Not Contain:

      Free of Artificial Flavors, Free of Artificial Colors

      How Do You Read A Supplement Facts Label?

      Specifications

      Brand:
      The Vitamin Shoppe
      Form:
      Tablet(s)
      Serving Size:
      2 Tablets
      Number of Servings:
      300 Servings
      Price per Serving:
      ($0.19 / serving)
      Product Weight:
      23  OZ
      Allergens:
      Soy Free, Tree Nut Free
      Specialty Diets:
      Gluten Free ,  Dairy Free
      Item # :
      VS-2175 / 1307284

      Product Reviews
         (117)

      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      117 Ratings
      3.9out of 5 stars
      117 Ratings

      Rated 5 stars by 65% of reviewers

      565%

      Rated 4 stars by 6% of reviewers

      46%

      Rated 3 stars by 5% of reviewers

      35%

      Rated 2 stars by 5% of reviewers

      25%

      Rated 1 star by 19% of reviewers

      119%
      Would you recommend?
      1-10 of 117 Reviews
      • checkMost Recent
      • Most Helpful
      • Oldest
      • Highest Rated
      • Lowest Rated
      • (76)
      • (7)
      • (6)
      • (6)
      • (22)
      • Under 18 (0)
      • 18-24 (0)
      • 25-34 (5)
      • 35-44 (5)
      • 45-54 (13)
      • 55-64 (9)
      • 65+ (12)
      Customers talk about
      AI analysis found these key themes mentioned in reviews.
      Sep 8, 2026
      Rated 5 out of 5
      RECOMMEND This Brand of Multi-Enzymes.
      I have been using This brand of Multi-Enzyme Digestive Formula for 9 years. After having my
      Pancreas removed.- Pancreatectomy. It has the Enzymes my body need to function correctly. Checking each time the formula remains the same. Recommend it and thankful it remains available. I Count on my order being fill and delivered correctly. If some isn't correct The Vitamin shoppe fixes the order quickly.
      dorothy mVerified Purchaser
      Location
      US
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Mar 30, 2025
      Was this helpful?
      Review by dorothy m has been flagged
      Flag
      Jul 26, 2026
      Rated 5 out of 5
      It's good. I only use when needed & it works.
      Best general enzymes for heavy meals or food with weird additives or lactose . Sometimes helps with bloating and heartburn.
      M AVerified Purchaser
      Location
      Charlotte, NC, US
      Gender
      Male
      Age Range
      25-34
      Would you recommend?:Yes
      Purchased on Aug 10, 2025
      Was this helpful?
      Review by M A has been flagged
      Flag
      Jan 8, 2026
      Rated 5 out of 5
      This is the best product for digestive issues
      I started taking this a couple of years after I had my gallbladder removed. The Naturopathic Doctor had suggested that I take a product that had lipase to help with the break down of fried foods and other foods.
      It took me a while to really appreciate this product and it is now part of my daily regimen. I have found this multi enzyme supplement to be very helpful in the most unexpected ways, like when I ate something that quite agree with my body.
      undefined uVerified Purchaser
      Purchased on Dec 23, 2025
      Was this helpful?
      Review by undefined u has been flagged
      Flag
      Jul 11, 2025
      Rated 5 out of 5
      It started working on day 1
      I carry these with me because the belly pressure and bloating without them is getting unbearable. They have really helped tremendously already, and I'm only on day 2.
      When I first opened the bottle, I was not knocked out by an overwhelming smell; I didn't notice a smell at all. I was pleasantly surprised by the slight peppermint taste, but they aren't in my mouth long enough to really make it or break it for me. I seriously don't know what the fuss over the smell is about. They're pills. Not all pills smell or taste good. These aren't bad.
      SHANNON FVerified Purchaser
      Location
      Little Chute, WI, US
      Gender
      Female
      Age Range
      55-64
      Would you recommend?:Yes
      Purchased on Jul 3, 2025
      Was this helpful?
      Review by SHANNON F has been flagged
      Flag
      Jul 4, 2025
      Rated 5 out of 5
      Satisfied
      I have taken this after meals, and it appeared to help with digestion. Will take again as it contains the needed enzymes and I feel this is better than a probiotic.
      RICHARD K
      Location
      FL, US
      Gender
      Male
      Age Range
      65+
      Would you recommend?:Yes
      Was this helpful?
      Review by RICHARD K has been flagged
      Flag
      Oct 18, 2024
      Rated 1 out of 5
      Watch out if you are Celiac patient.
      Be careful Here! It says Gluten Free but when I took this product had multiple diarrhea episodes. Thought maybe it was bad food and tried again with same results. Then I read with magnifier , on bottle it lists Wheat under contents. I live 44.5 miles from nearest store and I was told I was outside the 30 day return policy. We have just had2 hurricanes in last month, you would think some help would be forthcoming.
      Karen W
      Location
      Crystal River, FL, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:No
      Was this helpful?
      Review by Karen W has been flagged
      Flag
      May 30, 2024
      Rated 1 out of 5
      Severe constipation
      This product caused severe constipation in my ascending colon. No matter how I took it or reduced taking it, it still caused constipation. I do not recommend!
      yolanda HVerified Purchaser
      Location
      Bristol, TN, US
      Gender
      Female
      Age Range
      45-54
      Would you recommend?:No
      Purchased on Dec 27, 2021
      Was this helpful?
      Review by yolanda H has been flagged
      Flag
      May 24, 2024
      Rated 2 out of 5
      Causes constipation
      Causes constipation.
      yolanda H
      Location
      Bristol, TN, US
      Gender
      Female
      Age Range
      45-54
      Would you recommend?:No
      Was this helpful?
      Review by yolanda H has been flagged
      Flag
      Jan 22, 2024
      Rated 1 out of 5
      HORRIBLE!!
      This is the most HORRIBLE tasting enzyme that I had to spit it out of my mouth!! It was beyond God Awful!! There was no peppermint flavor at all. Don't know how anyone can stand these?
      Julie B
      Location
      Wellborn, FL, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:No
      Was this helpful?
      Review by Julie B has been flagged
      Flag
      Oct 24, 2023
      Rated 5 out of 5
      Great multi enzyme
      Great way to assimilate all your nutrients and a must for Thanksgiving when you're over eat
      JORGE SVerified Purchaser
      Location
      Miami, FL, US
      Gender
      Male
      Age Range
      45-54
      Would you recommend?:Yes
      Purchased on Apr 3, 2014
      Was this helpful?
      Review by JORGE S has been flagged
      Flag
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      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      1 Question
      Why did you choose this?
      The Vitamin ShoppeStore

      works

      Salem GAug 22, 2026

      Great digestive

      SELBY L TJul 18, 2026

      I was told several years ago that my body needed this, so I’ve been taking it ever since

      ALVA JEAN CMay 18, 2026

      I’ve used it before and think it works really well.

      CINDY HMay 10, 2026
      Questions for Similar Products
      Are the tablets supposed to be swallowed or chewed?
      Multi Enzyme
      About
      Multi Enzyme
      A shopperJun 16, 2013

        I tried chewing one and it was so unpalatable I'll never try again. It has a somewhat slick surface, which makes it easy to swallow. I believe the enzymes are to do their work in the stomach rather than in the mouth, so it wouldn't be important to chew them.

      Joan HJun 16, 2013
      Reply
      Inaccurate
      Answer by Joan H has been flagged

        swallowed, however, always have a bite or two of food first. NEVER on an empty stomach, this is because of the Betaine HCL.. Karl Waterman, DNM

      Karl WJun 16, 2013
      Reply
      Inaccurate
      Answer by Karl W has been flagged

        The tablets should be swallowed, preferably with warm water.

      Christopher DJun 17, 2013
      Reply
      Inaccurate
      Answer by Christopher D has been flagged

        The tablets are supposed to be swallowed.

      Richard HJun 18, 2013
      Reply
      Inaccurate
      Answer by Richard H has been flagged

        I was swallowed

      inoue tJun 18, 2013
      Reply
      Inaccurate
      Answer by inoue t has been flagged

        Swallowed

      Weldon HJun 17, 2013
      Reply
      Inaccurate
      Answer by Weldon H has been flagged

        swallowed

      Janet HJun 17, 2013
      Reply
      Inaccurate
      Answer by Janet H has been flagged

        swallowed

      karen lJun 16, 2013
      Reply
      Inaccurate
      Answer by karen l has been flagged

      Vote for the best answer above!

      how big is pill?
      Multi Enzyme
      About
      Multi Enzyme
      A shopperAug 12, 2015

        Slightly larger than a circular aspirin pill and about 1 1/2 as thick. It is worth taking because it works very well for digestion.

      pamela hAug 12, 2015purchased Sep 9, 2013
      Reply
      Inaccurate
      Answer by pamela h has been flagged

        It's 1/2" in diameter and about 3/16" thick. They are easy to swallow.
      I usually take 2 at a time. Hope this helps.

      DONNA KAug 13, 2015purchased Jan 21, 2013
      Reply
      Inaccurate
      Answer by DONNA K has been flagged

        The VS enzyme I take is a pill as previously described, not a capsule. VS online may show a picture. Look it up.

      pamela hAug 12, 2015purchased Sep 9, 2013
      Reply
      Inaccurate
      Answer by pamela h has been flagged

        Maybe a quarter of an inch.
      There might be some chewables.
      I've been taking these for years. They work great

      Virginia HAug 12, 2015purchased Dec 30, 2012
      Reply
      Inaccurate
      Answer by Virginia H has been flagged

        They also have a slick exterior as if coated to make for easier swallowing.

      pamela hAug 12, 2015purchased Sep 9, 2013
      Reply
      Inaccurate
      Answer by pamela h has been flagged

        bigger than a baby aspirin, but smaller than those large fish oil capsules

      Jennifer MAug 12, 2015purchased Sep 12, 2013
      Reply
      Inaccurate
      Answer by Jennifer M has been flagged

        A little longer than a pinkie nail - but a capsule, and easy to swallow

      Carol DAug 12, 2015purchased Jan 13, 2015
      Reply
      Inaccurate
      Answer by Carol D has been flagged

        One-half inch in diameter and 3/8 inch thick. Surface is smooth.

      Laurie GAug 12, 2015purchased Sep 5, 2013
      Reply
      Inaccurate
      Answer by Laurie G has been flagged

        It is a round tablet, 1/2" in diameter and about 7/16" thick.

      John DAug 12, 2015purchased Sep 13, 2013
      Reply
      Inaccurate
      Answer by John D has been flagged

        It is round and the size of a normal aspirin

      Mary Jo EAug 12, 2015purchased Sep 1, 2013
      Reply
      Inaccurate
      Answer by Mary Jo E has been flagged

      Vote for the best answer above!

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      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
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      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
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      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.