Free shipping on $45+, or pick up in-store
NEW LIMITED-TIME FLAVORS! Bubblicious Strawberry Splash and Original from GHOST® ENERGY
Buy One, Get One 50% Off Alani Nu Energy Cases
Earn FREE points for faster Cash Back Awards. This Month's Secret Code is SUNNYDAY
Cholestene with Red Yeast Rice - 1,200 MG (120 Capsules)

Cholestene with Red Yeast Rice - 1,200 MG (120 Capsules)

AUTO DELIVERY SAVE 15%

Shop All HPF LLC

Cholestene with Red Yeast Rice - 1,200 MG (120 Capsules)

Rated 4.9 out of 5
68 Reviews|4 Questions | 208 Answers|
Zoom Icon

AUTO DELIVERY SAVE 15%

Delivery Options
Same-Day Delivery +$8.99 / delivery to 1105 Update Zip Code
Unfortunately, we are unable to offer Same-Day Delivery in your area.

Earn Points on This!
or Healthy Awards® to earn points on every purchase towards Cash Back Awards.

Customers Also Viewed

About This Product

To be used as part of your cholesterol management program. Red Yeast is known to promote HMG-CoA reductase inhibition action which may help to promote healthy cholesterol levels.

Read More

Directions

Take 2 capsules twice a day with food. Store at 15-30C (59-86F). Protect from heat, light and moisture.

Warning

Do not use if pregnant or nursing, or have a history of liver disease, are an organ transplant recipient, or have had major surgery. within the last 8 weeks. Discontinue use if you experience any unexplained muscle pain or tenderness, especially if accompanied by flu-like symptoms. Not intended to be taken by anyone under the age of 18. Keep out of reach of children. Do not purchase if seal is broken.

Updated Jan 15, 2026
Read More
Serving Size: 2 Capsules
Number of Servings: 60 Servings
Amount Per Serving
% Daily Value
RED YEAST RICE  - (FROM TRADITIONAL FERMENTATION OF MONASCUS PURPUREUS WENT)
N/A*

Other Ingredients:

Gelatin.

Brand:
HPF LLC
Form:
Capsules
Strength:
1200 MG
Serving Size:
2 Capsules
Number of Servings:
60 Servings
Price per Serving:
($0.40 / serving)
Product Weight:
4  OZ
Item # :
PP-2008 / 1066515
68 Ratings
4.9out of 5 stars
68 Ratings

Rated 5 stars by 96% of reviewers

Rated 4 stars by 3% of reviewers

Rated 3 stars by 0% of reviewers

Rated 2 stars by 0% of reviewers

Rated 1 star by 1% of reviewers

Would you recommend?
1-10 of 68 Reviews
Rated 1 out of 5
May 20, 2026
Horrible side effects
Horrible side effects. I never knew a supplement could have so many horrible side effects. Daily headaches, muscle aches, etc. Threw mine in the trash.
Karen Fox
Rated 5 out of 5
May 13, 2026
Thanks to HPF Cholestene
Thanks to HPF Cholestene, my LDL numbers are low enough to keep my doctor off my back. Other brands of RYR have not worked for me.
Laura Charron
Rated 5 out of 5
May 10, 2026
Used for years
Used for years. Price keeps increasing.?
Rosalie Daversa
Rated 5 out of 5
May 4, 2026
Was having a hard time ordering this from another co
Was having a hard time ordering this from another co. So was pleasantly pleased with my order from your company
Laura Stevens
Rated 5 out of 5
May 4, 2026
it works 100%
I have been using this for years,it keeps my cholesterol low,I once bought another brand and my cholesterol went sky high?.i only recommend Cholestene,I have had zero side effects?.but it's best to stop taking them if you are on antibiotic,it effects your liver enzymes?I keep a stock in I am afraid to be out of them .
Francesca
Rated 5 out of 5
May 2, 2026
Great Stuff!
HPF Cholestene is great stuff, lowers cholesterol, and triglycerides.
Arthur Shiels
Rated 5 out of 5
May 2, 2026
nothing comes close
On a scale of 1-10 this product is a 10. The second best red yeast rice product on that same scale would be a 2. If I couldn't use this, I wouldn't use any. And my lab results prove to me that it works.
Mark Austin
Rated 5 out of 5
Mar 10, 2026
Actually a NP had given it to me to try and it worked
Actually a NP had given it to me to try and it worked, helping lowering my BP, so I decided to get it for myself.
Joanne Johnson
Rated 5 out of 5
Feb 14, 2026
It's agreat project at a good price
It's agreat project at a good price. Thanks
Toby Rosenberg
Rated 5 out of 5
Feb 7, 2026
Arrived quickly and well packaged
Arrived quickly and well packaged, I can't wait to see how my labs will lookin 3 months
Thea bea
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

We'll email them your question, then email you their replies.

Have a question? Ask owners.Have a question about this? Ask people who own it.
Start typing and see existing answers.
4 Questions
Why did you choose this?
The Vitamin ShoppeStore

recommended

Mary S

Doctor recommended

Jan L

Recommended online

Sharon L

Dr recommended

Mary S
My doctor told me to take one tablet of Chinese red rice yeast 600 mg at bedtime for 4 weeks. Originally I had bought Vitamin Shoppe brand at 1200 mg (which he had originally told me to get) but the pills were too big and I have a problem swallowing. Do you have either a 600 mg tablet of either Cholestene or your Vitamin Shoppe brand? I'm wondering if he made a mistake on the dosage and meant 1200 mg daily. Everyone seems to be on a regimen of 4 1200 mg daily. Thanks for your reply and I will wait to purchase until I hear. Much appreciate your time.
A shopper
Did anyone experience side effects with this product? Any headaches or muscle pain or elevated liver enzymes?
Liza R

Best Answer:  I I have taken this product since it was introduced in I think the 1990s. I take 2400 mg per day because my cholesterol is naturally 300. It reduced My cholesterol to190 and my LDL from 1:80 to 120 with no side effects.

I had an angiogram of my heart a year ago. My heart arteries were almost clear.

Cholestine blocks cholesterol produced in the liver. You can also take plant sterols that work differently absorbing cholesterol from the food you eat to lower it further.

Paul A
Do I need to take CoQ10 with Cholestene?
Ann D

Best Answer:  No. It is an excellent product though. My husband and I have taken it at one time or another but you do not have to take it with the Cholestene. JC

Judy C
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

 

FREE STANDARD SHIPPING on orders of $45 or more

How to get FREE Standard Shipping:

  1. Ship to an address within the United States (including U.S. territories)
  2. Place your online order of $45 or more* - after promotions and before tax are applied
  3. Use "Standard" shipping option at checkout

Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

 

*Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

 

Orders for states outside of the continental U.S. (including those of $45 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

back to top
Looking For More
Related Products
  • KAL
    Red Yeast Rice, CoQ10 & Omega 3 - 600 MG / 30 MG / 500 MG (60 Softgels)
    Red Yeast Rice, CoQ10 & Omega 3 -

    The KAL® brand offers this incredible combination of 600mg Red Yeast Rice and 30 mg CoQ-10 in a base of 500 mg Omega # Fish Oil.

    This easy-to-swallow, once daily softgel provides triple support for a normal, healthy lifestyle.

    Red Yeast Rice contains beneficial unsaturated fatty acids including mono and polyunsaturated fatty acids, as well as proteins, amino acids and phytonutrients.

    CoQ-10 is intended to provide nutritive support for antioxidant activity, as well as other potential health benefits.
    The Omega 3 Fish Oil is a source of essential fatty acids EPA & DHA and is molecularly distilled.
    1 Daily
    600/30/500mg
    Molecularly Distilled Fish Oil

    Rated 5.0 stars out of 5 stars, From 5 customer reviews 
    $42.99
    Add To Cart
  • Life Seasons
    Choles-T Cholesterol Support with Red Yeast Rice, CoQ-10 & More (90 Vegetarian Capsules)
    Choles-T Cholesterol Support with Red Yeast Rice, CoQ-10

    Cholest-T™ Cholesterol Support

    ♦ Supports cholesterol and triglyceride levels already within the normal range.

    ♦ Promotes cardiovascular function.

    ♦ Supports healthy liver function.

    ♦ Certified Gluten Free

    ♦ No Magnesium Stearate

    ♦ Vegetarian Formula

    For Life's changes of seasons, there's LifeSeasons®.

    Every new season brings change. It's the cycle of life that renews and energizes. LifeSeasons® offers a brand of supplements designed to support both your daily nutritional needs plus specific health concerns.

    This Best in Class formulation includes premium ingredients to support healthy liver function and maintain cholesterol and triglyceride levels already within a normal range.

    Red Yeast Rice - Supports cholesterol levels already within the normal range

    Cholesstrinol HP™ - Helps maintain cholesterol and triglyceride levels already within the normal range.

    Guggulipids - Provides support for healthy liver functions.

    Phytosterol 90% (Beta Sitosterol 40%) - Plant sterols that help support cholesterol levels already within the normal range.

    Co Q10 - Helps boost energy, enhance the immune system, and has powerful antioxidant properties.

    Rated 4.0 stars out of 5 stars, From 9 customer reviews 
    $34.99
    Add To Cart
  • Natures Plus
    Organic Whole Food Red Yeast Rice (60 Vegan Capsules)
    Organic Whole Food Red Yeast Rice (60 Vegan

    Nature's Plus® Source of Life Garden® Red Yeast Rice is the world's first, fully certified organic, red yeast rice capsule supplement, delivering 600 mg of standardized nutritional activity. With USDA organic certification and manufactured by Nature's Plus in an independently certified GMP facility, this supplement delivers 2.3 mg of total monacolins per capsule, making it exceptional in the organic supplements market. Experience the difference that Nature's Plus Source of Life Garden, high-quality, certified organic Red Yeast Rice can make for your overall well-being! Nature's Plus Source of Life Garden Red Yeast Rice includes all of the high-quality features intrinsic to all Nature's Plus Garden Supplements:

    • USDA Organic Certification
    • Non-GMO Ingredients
    • Tested to be Gluten Free
    • Made in an Independently Certified GMP Facility

    Nature's Plus Source of Life Garden Organic Red Yeast Rice is made from the highest quality, certified organic red yeast rice available, delivering the superior activity and unmatched results you deserve.

    Rated 5.0 stars out of 5 stars, From 2 customer reviews 
    $26.99
    Add To Cart
  • Natures Plus
    Red Yeast Rice Minis - Extended Release - 600 MG (120 Mini Vegetarian Tablets)
    Red Yeast Rice Minis - Extended Release -

    Nature's Plus Herbal Actives Red Yeast Rice extract is uniformly standardized to a minimum of 1.7% (10.2 mg) total monacolins. Each tablet is a revolutionary extended-release system that provides rapid and sustained results. Providing the greatest concentration of active botanical principles, Herbal Active Red Yeast Rice maximizes the synergistic benefits of the whole extract.

    • Guaranteed Maximum Potency: Each Herbal Actives formula is scientifically standardized to the highest level of active principles.
    • HerbaShield: An exclusive purity and safety system providing light-resistant bottle, airtight inner seal, moisture-absorbing packet, tamper-evident safety cap and tamper-proof full bottle seal.
    • Extended Release Mini-Tabs
    • Prescription Quality
    • Vegetarian
    • Easy to Swallow
    Rated 5.0 stars out of 5 stars, From 5 customer reviews 
    $47.99
    Add To Cart
Related Searches

More Products For Your Wellness Journey

BrandHPF LLC
Health ConcernsCholesterol Support
HomeVitamins & SupplementsSupplementsCholestene with Red Yeast Rice - 1,200 MG (120 Capsules)
Page loadingLOADING...
Page loadingLOADING...
back to top