Methylcobalamin (Methyl B-12) is better absorbed and retained than other forms of B12 (such as cyanocobalamin). Methyl B12 protects nerve tissue and brain cells, and promotes better sleep and recycles (via methylation) homocysteine, an oxidizing metabolite, back into the amino acid methionine. Also vegetarians/vegans often required B12 supplementation.

Pantethine is a derivative of vitamin B5. Pantethine supports lipid metabolism by its ability to raise levels of CoA, a cofactor involved in several metabolic pathways including carbohydrate and lipid metabolism.** CoA combines with acetyl groups to form Acetyl CoA, a participant in energy production.**

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