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5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)

5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)

$19.99
($0.33/serving)

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5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)

Rated 4.3 out of 5
16 Reviews7 Questions153 Answers
Gluten FreeDairy FreeSoy FreeTree Nut Free
$19.99
($0.33/serving)

BOGO

BUY ONE, GET ONE 50% OFF

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Product Info

About This Product

  • Provides mood support
  • Free of gluten, dairy, soy, nuts, sugar, salt, preservatives, and artificial colors or flavors

We all need a little pick-me-up from time to time. Designed to support a positive mood, The Vitamin Shoppe® brand 5-HTP with Vitamin B6 is a great go-to when you're experiencing the occasional blues.

This feel-good formula features 5-hydroxytryptophan—which gets converted into serotonin in the brain, and vitamin B6—which is required for making neurotransmitters like serotonin.

Read More

Directions

Take one (1) capsule daily, preferably in between meals.

Warning

Do not use this product if you are pregnant or nursing or taking any antidepressantmedications such as selective serotonin reuptake inhibitors (SSRI's), tricyclic antidepressants or monamine oxidase inhibitors (MAOI). Consult your physician prior to use if you have any medical condition or are taking any medications. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

Supplement Facts

Serving Size: 1 Capsule(s)
Number of Servings: 60 Servings
Amount Per Serving
% Daily Value
VITAMIN B6  - (FROM PYRIDOXINE HCI)
1176%
CALCIUM  - (AS CALCIUM PHOSPHATE)
5%
PHOSPHORUS  - (AS DICALCIUM PHOSPHATE)
4%
5-HYDROXYTRYPTOPHAN  - (FROM GRIFFONIA SIMPLICIFOLIA) (SEED)
N/A*

Other Ingredients:

Microcrystalline cellulose, gelatin, magnesium stearate, silicon dioxide.

Does Not Contain:

Preservative Free, Free of Artificial Flavors, Free of Artificial Colors

Specifications

Brand:
The Vitamin Shoppe
Form:
Capsules
Strength:
100 MG
Serving Size:
1 Capsule(s)
Number of Servings:
60 Servings
Price per Serving:
($0.33 / serving)
Product Weight:
2  OZ
Allergens:
Soy Free, Tree Nut Free
Specialty Diets:
Gluten Free ,  Dairy Free
Item # :
VS-2283 / 1560655

Product Reviews
   (16)

16 Ratings
4.3out of 5 stars
16 Ratings

Rated 5 stars by 69% of reviewers

Rated 4 stars by 12% of reviewers

Rated 3 stars by 6% of reviewers

Rated 2 stars by 6% of reviewers

Rated 1 star by 6% of reviewers

1-10 of 16 Reviews
Mar 31, 2026
Rated 3 out of 5
My honest review
It's ok, it's better take at night due to the sleepy effect it gives off. If u take in the morning you may feel very tired throughout the day. It can cause headaches. I started off with 100mg I recommend starting with 50mg for beginners. Haven't really seen improvement yet. But it's good for nigh time if u have trouble sleeping
Zack BVerified Purchaser
Location
Long Island, NY, US
Gender
Male
Age Range
18-24
Would you recommend?Yes
Purchased on Jan 11, 2026
Was this helpful?
Jan 19, 2025
Rated 5 out of 5
Works well for mild depression or PMS
I found this helpful for depression symptoms and much more effective than SAMe.
Emerald NVerified Purchaser
Location
CA, US
Gender
Female
Age Range
35-44
Would you recommend?Yes
Purchased on Aug 10, 2017
Was this helpful?
Aug 27, 2024
Rated 1 out of 5
Major ACNE BREAKOUT!
This made my face breakout like crazy. I believe that the 1176% daily value of vitamin B6 is the culprit.
Jonathan S
Location
New York, NY, US
Gender
Male
Age Range
35-44
Would you recommend?No
Was this helpful?
Oct 24, 2023
Rated 5 out of 5
Feel good be happy
This is a must to deal with stress make you feel happy and help you go to sleep at night. I also like to take it with my coffee in the morning with some extra taurine.
JORGE SVerified Purchaser
Location
Miami, FL, US
Gender
Male
Age Range
45-54
Would you recommend?Yes
Purchased on Apr 14, 2018
Was this helpful?
Sep 20, 2023
Rated 2 out of 5
Not for people prone to acne due to b6
Been taking it for a few months. Was helping my mood. But my face has been breaking out for the same duration. I tried looking at everything as to why and just noticed today the absurd amount of b6 in this. Since im not choosing between mood and acne, which brings my mood down anyway, my half full bottle and new bottle are going to be trashed
Chris PVerified Purchaser
Age Range
25-34
Would you recommend?Yes
Purchased on Aug 1, 2023
Was this helpful?
Sep 19, 2023
Rated 5 out of 5
helpful
Like the size and quality
Beth ZVerified Purchaser
Purchased on Aug 12, 2023
Was this helpful?
Feb 18, 2023
Rated 5 out of 5
It works
I bought it to take with my Zoloft for that reason xtra boost of seratonin and it works
JedenaVerified Purchaser
Purchased on Jan 11, 2023
Was this helpful?
Jul 21, 2020
Rated 5 out of 5
5 HTP with Vit B6
Works fine....
Ronald MVerified Purchaser
Location
Carol Stream , IL, US
Gender
Male
Age Range
65+
Would you recommend?Yes
Purchased on Jun 2, 2020
Was this helpful?
Jul 14, 2020
Rated 5 out of 5
Prompt delivery
Accurate product, amazingly prompt delivery.
CATHLEEN GVerified Purchaser
Location
Shoreline, WA, US
Gender
Female
Age Range
65+
Would you recommend?Yes
Purchased on Apr 21, 2020
Was this helpful?
Oct 11, 2019
Rated 5 out of 5
Its good
I like these medicine works good
Nathalie GVerified Purchaser
Location
Lakeland, FL, US
Gender
Female
Age Range
45-54
Would you recommend?Yes
Purchased on Sep 11, 2019
Was this helpful?
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

Q&A

We'll email them your question, then email you their replies.

Have a question? Ask owners.Have a question about this? Ask people who own it.
Start typing and see existing answers.
5 Questions
Why did you choose this?
The Vitamin ShoppeStore

Recommendation

Michkayla A

Great pills to sleep!

Liza A S

to help me sleep

JAN T

Helps me fall asleep fast and stay asleep

Linda G
What is this used for?
A shopper

  It helps to regulate and support moods. The lows are not as low and the highs still feel great. It can control appetite because it regulates your moods. NOT like a narcotic! Definitely recommend. It is the one supplement I do not skip.

Suzanne F

  5-HTP is a serotonin precursor. It is naturally occurring in the body but with age diminishes in quantity. It helps with low grade depression, sleep and energy, in my personal experience.

Peter K

Vote for the best answer above!

How/when do you take this for insomnia? Does it affect your weight?
Rhonda

  I take it at night before bed (try one hour before or right at bedtime and then whatever works stick with the same time taking it and going to bed each night to get in a routine). No it does not normally affect weight. If you struggle with weight gain, and have low serotonin levels, it should help you lose it over time by establishing proper serotonin levels-and getting proper rest of course will help too.I hope it works for you as it does me!!

Andrea J

  Take it about an hour before sleepIf you sleep well this can increase your natural human growth hormone which improves your metabolism and could lead to some weight lass If that is what you need.

Carole D

  I don't take it for insomnia, but I do take one in the am. It does not affect my weight i.e. weight gain. If it did, I wold not be happy.

Patricia J

  I take 5-HTP about one hour before bedtime. It has not affected my weight. No problems at all!

Denise K

  Both for mood. No notable weight effect. Will get more when I can afford it.

Mary M

Vote for the best answer above!

Has anyone used this while on statins?
Lester D

  I can not answer this question as I do not take any statins. I take this product as a mood enhancer, as with any supplements I use,I consult my doctor. This is a question for her doctor to answer.

Helen W

  My husband takes 5 htp but he doesn't take any statin drugs . So I'm sorry we can't help you. I would ask your doctor, a P.A. or a pharmacist. They would know. Good luck.

Angela M

  I haven't and I would strongly suggest that you ask your doctor,or at least your pharmacist, before taking any supplement with medication.

Rebecca C C

Vote for the best answer above!

Does this work for children with ADHD?
A shopper

Best Answer:  I don't know, as I don't have any children with ADHD; however, I would encourage you to discuss use of the product with your child's pediatrician to see if there are any contraindications for using this product.

Angela W
Questions for Similar Products
Where is it actually made, and from where are the actual ingredients?
5-HTP With Vitamin B6
About
5-HTP With Vitamin B6
Ronald O

  The Vitamin Shoppe should be able to provide the answers to your questions, Ronald. After all, it is their products that we are buying, right? I used this product at bedtime to give me a better quality of sleep. It appears to be effective.Good luck.

Lillie B

Vote for the best answer above!

Has anyone used this while on statins?
5-HTP With Vitamin B6
About
5-HTP With Vitamin B6
A shopper

  I take this with a beta blocker with no issues. A store associate checked for interactions for me before I purchased. I would call customer service and ask them to check for you if you haven't already. Works great for me, I take it for anxiety / positive mood.

Rebecca S

  Yes; no problems.

Robert P

Vote for the best answer above!

Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

Shipping Info

 

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Orders for states outside of the continental U.S. (including those of $45 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

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