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5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)

5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)

$19.99
($0.33/serving)

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5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)

Rated 3.9 out of 5
10 Reviews|5 Questions | 150 Answers|
Boiron Histaminum Hydrochloricum 30C pellets view
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Boiron Silicea 30C for Fatigue and Irritability
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      Gluten FreeDairy FreeSoy FreeTree Nut Free
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      $19.99
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      • 100 MG
      • 60 Capsules$19.99
      • 120 Capsules$34.99
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      These products are dietary supplements and are not intended to diagnose, treat cure or prevent any disease. Reviews are not intended as a substitute for appropriate medical care or the advice of a physician or another medical professional. Actual results may vary among users. Vitaminshoppe.com makes no warranty or representation, expressed or implied, as to the accuracy or validity of the information contributed by outside product review submissions, and assumes no responsibility or liability regarding the use of such information. The information and statements regarding the dietary supplements have not been evaluated by the Food and Drug Administration. If you have a medical condition or disease, please talk to your health care provider. If you are currently taking a prescription medication, you should work with your health care provider before discontinuing any drug or altering any drug regimen, including augmenting your regimen with dietary supplements. Do not attempt to self-diagnose any disease or ailment based on the reviews and do not use the information contained herein for diagnosing or treating a health problem or disease. Proper medical care is critical to good health. If you have a health concern or suspect you have an undiagnosed sign or symptom, please consult a physician or health care practitioner. Online product reviews are a useful resource for, but The Vitamin Shoppe believes that customers who rely on those reviews should get a true and accurate picture of what other customers think. For that reason, we put procedures in place to ensure the reviews you see are real and honest. Additionally, we won't edit reviews to alter the message and we will always treat positive and negative reviews equally.
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      5-HTP with Vitamin B6 for Mood Support - 100 MG (60 Capsules)
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      Product Info

      About This Product

      • Provides mood support
      • Free of gluten, dairy, soy, nuts, sugar, salt, preservatives, and artificial colors or flavors

      We all need a little pick-me-up from time to time. Designed to support a positive mood, The Vitamin Shoppe® brand 5-HTP with Vitamin B6 is a great go-to when you're experiencing the occasional blues.

      This feel-good formula features 5-hydroxytryptophan—which gets converted into serotonin in the brain, and vitamin B6—which is required for making neurotransmitters like serotonin.

      Read More

      Directions

      Take one (1) capsule daily, preferably in between meals.

      Warning

      Do not use this product if you are pregnant or nursing or taking any antidepressantmedications such as selective serotonin reuptake inhibitors (SSRI's), tricyclic antidepressants or monamine oxidase inhibitors (MAOI). Consult your physician prior to use if you have any medical condition or are taking any medications. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

      Updated Jan 15, 2026
      Read More

      Supplement Facts

      Serving Size: 1 Capsule
      Number of Servings: 60 Servings
      Amount Per Serving
      % Daily Value
      VITAMIN B6  - (FROM PYRIDOXINE HCI)
      20 MG
      1176%
      CALCIUM  - (AS CALCIUM PHOSPHATE)
      70 MG
      5%
      PHOSPHORUS  - (AS DICALCIUM PHOSPHATE)
      54 MG
      4%
      5-HYDROXYTRYPTOPHAN  - (FROM GRIFFONIA SIMPLICIFOLIA) (SEED)
      100 MG
      N/A*

      Other Ingredients:

      Microcrystalline cellulose, gelatin, magnesium stearate, silicon dioxide.

      Does Not Contain:

      Preservative Free, Free of Artificial Flavors, Free of Artificial Colors

      How Do You Read A Supplement Facts Label?

      Specifications

      Brand:
      The Vitamin Shoppe
      Form:
      Capsules
      Strength:
      100 MG
      Serving Size:
      1 Capsule
      Number of Servings:
      60 Servings
      Price per Serving:
      ($0.33 / serving)
      Product Weight:
      2  OZ
      Allergens:
      Soy Free, Tree Nut Free
      Specialty Diets:
      Gluten Free ,  Dairy Free
      Item # :
      VS-2283 / 1560655

      Product Reviews
         (10)

      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

      10 Ratings
      3.9out of 5 stars
      10 Ratings

      Rated 5 stars by 50% of reviewers

      550%

      Rated 4 stars by 20% of reviewers

      420%

      Rated 3 stars by 10% of reviewers

      310%

      Rated 2 stars by 10% of reviewers

      210%

      Rated 1 star by 10% of reviewers

      110%
      Would you recommend?
      10 Reviews
      • checkMost Recent
      • Most Helpful
      • Oldest
      • Highest Rated
      • Lowest Rated
      • (5)
      • (2)
      • (1)
      • (1)
      • (1)
      • Under 18 (0)
      • 18-24 (1)
      • 25-34 (1)
      • 35-44 (2)
      • 45-54 (1)
      • 55-64 (0)
      • 65+ (1)
      Mar 31, 2026
      Rated 3 out of 5
      My honest review
      It's ok, it's better take at night due to the sleepy effect it gives off. If u take in the morning you may feel very tired throughout the day. It can cause headaches. I started off with 100mg I recommend starting with 50mg for beginners. Haven't really seen improvement yet. But it's good for nigh time if u have trouble sleeping
      Zack BVerified Purchaser
      Location
      Long Island, NY, US
      Gender
      Male
      Age Range
      18-24
      Would you recommend?:Yes
      Purchased on Jan 11, 2026
      Was this helpful?
      Review by Zack B has been flagged
      Flag
      Aug 27, 2024
      Rated 1 out of 5
      Major ACNE BREAKOUT!
      This made my face breakout like crazy. I believe that the 1176% daily value of vitamin B6 is the culprit.
      Jonathan S
      Location
      New York, NY, US
      Gender
      Male
      Age Range
      35-44
      Would you recommend?:No
      Was this helpful?
      Review by Jonathan S has been flagged
      Flag
      Oct 24, 2023
      Rated 5 out of 5
      Feel good be happy
      This is a must to deal with stress make you feel happy and help you go to sleep at night. I also like to take it with my coffee in the morning with some extra taurine.
      JORGE SVerified Purchaser
      Location
      Miami, FL, US
      Gender
      Male
      Age Range
      45-54
      Would you recommend?:Yes
      Purchased on Apr 14, 2018
      Was this helpful?
      Review by JORGE S has been flagged
      Flag
      Sep 20, 2023
      Rated 2 out of 5
      Not for people prone to acne due to b6
      Been taking it for a few months. Was helping my mood. But my face has been breaking out for the same duration. I tried looking at everything as to why and just noticed today the absurd amount of b6 in this. Since im not choosing between mood and acne, which brings my mood down anyway, my half full bottle and new bottle are going to be trashed
      Chris PVerified Purchaser
      Age Range
      25-34
      Would you recommend?:Yes
      Purchased on Aug 1, 2023
      Was this helpful?
      Review by Chris P has been flagged
      Flag
      Feb 18, 2023
      Rated 5 out of 5
      It works
      I bought it to take with my Zoloft for that reason xtra boost of seratonin and it works
      JedenaVerified Purchaser
      Purchased on Jan 11, 2023
      Was this helpful?
      Review by Jedena has been flagged
      Flag
      May 22, 2019
      Rated 5 out of 5
      Same benefits as other brands
      I was a little reluctant to try the Vitamin Shoppes 5-HTP w/ Vit B6 after using more expensive brands. But I did and now I purchase it exclusively, saving money when Vit Shoppe Brands are on sale and with my reward points!
      Laura KVerified Purchaser
      Location
      Hayden, ID, US
      Gender
      Female
      Age Range
      65+
      Would you recommend?:Yes
      Purchased on Apr 7, 2019
      Was this helpful?
      Review by Laura K has been flagged
      Flag
      Apr 24, 2019
      Rated 4 out of 5
      5 Htp w/B6
      We use it because it is gluten & dairy free but the price could be better because we use so many supplements for our Special Needs son.
      Scott CVerified Purchaser
      Location
      Point Pleasant, NJ, US
      Gender
      Female
      Age Range
      35-44
      Would you recommend?:Yes
      Purchased on Mar 9, 2019
      Was this helpful?
      Review by Scott C has been flagged
      Flag
      Jul 10, 2018
      Rated 5 out of 5
      Good
      It's effective
      Chandalae CVerified Purchaser
      Location
      VA
      Gender
      Female
      Would you recommend?:Yes
      Purchased on Jun 26, 2018
      Was this helpful?
      Review by Chandalae C has been flagged
      Flag
      Nov 12, 2015
      Rated 4 out of 5
      good value
      very effective
      mom of 5
      Location
      redlands
      Would you recommend?:Yes
      Was this helpful?
      Review by mom of 5 has been flagged
      Flag
      Nov 4, 2015
      Rated 5 out of 5
      I would buy this product
      It's good
      Elo
      Location
      Brownsville Tx
      Was this helpful?
      Review by Elo has been flagged
      Flag
      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      5 Questions
      Most Recent Question
      Oldest Question
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      Oldest Answer
      Why did you choose this?
      The Vitamin ShoppeStore

      Recommendation

      Michkayla AFeb 19, 2026

      Great pills to sleep!

      Liza A SNov 5, 2025

      to help me sleep

      JAN TOct 10, 2025

      Helps me fall asleep fast and stay asleep

      Linda GJul 15, 2025
      What is this used for?
      A shopperNov 26, 2014

      Best Answer:  It helps to regulate and support moods. The lows are not as low and the highs still feel great. It can control appetite because it regulates your moods. NOT like a narcotic! Definitely recommend. It is the one supplement I do not skip.

      Suzanne FNov 26, 2014
      Reply
      Inaccurate
      Answer by Suzanne F has been flagged
      How/when do you take this for insomnia? Does it affect your weight?
      RhondaFeb 9, 2013

      Best Answer:  I take it at night before bed (try one hour before or right at bedtime and then whatever works stick with the same time taking it and going to bed each night to get in a routine). No it does not normally affect weight. If you struggle with weight gain, and have low serotonin levels, it should help you lose it over time by establishing proper serotonin levels-and getting proper rest of course will help too.

      I hope it works for you as it does me!!

      Andrea JFeb 11, 2013
      Reply
      Inaccurate
      Answer by Andrea J has been flagged
      Has anyone used this while on statins?
      Lester DDec 6, 2013

      Best Answer:  I can not answer this question as I do not take any statins. I take this product as a mood enhancer, as with any supplements I use,I consult my doctor. This is a question for her doctor to answer.

      Helen WDec 8, 2013
      Reply
      Inaccurate
      Answer by Helen W has been flagged
      Does this work for children with ADHD?
      A shopperJun 20, 2016

      Best Answer:  I don't know, as I don't have any children with ADHD; however, I would encourage you to discuss use of the product with your child's pediatrician to see if there are any contraindications for using this product.

      Angela WJun 20, 2016purchased Sep 3, 2014
      Reply
      Inaccurate
      Answer by Angela W has been flagged
      Disclaimer:

      Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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      FREE STANDARD SHIPPING on orders of $45 or more

      How to get FREE Standard Shipping:

      1. Ship to an address within the United States (including U.S. territories)
      2. Place your online order of $45 or more* - after promotions and before tax are applied
      3. Use "Standard" shipping option at checkout

      Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

       

      *Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

       

      Orders for states outside of the continental U.S. (including those of $45 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

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      Thanks for joining the family. Now you get points on every purchase—towards Cash Back Awards—plus, access to the Rewards Center with free points activities every month, giveaways, and oh yeah… those 25 bonus points will be in your account by tomorrow.

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.
      ×

      AUTO DELIVERY
      Auto Delivery is the best way to put your wellness goals first—and enjoy huge savings every time! We’ll send your essentials at a pace you choose (switch it up any time).
      • Forever Savings: You’ll get 20% off The Vitamin Shoppe® and Vthrive The Vitamin Shoppe® brands, 15% off everything else. Every subscription order. Every time.
      • Never Run Out: Stay effortlessly stocked up with your essentials.
      • Easily Manage: Use our app to easily manage subscriptions.
      • Free Shipping on Refills: Zero cost to replenish products of $25 or more.
      • View Auto Delivery FAQs for additional information
      Rely on the
      Vitamin Shoppe® 100% Satisfaction Guarantee
      Free shipping applies to Auto Delivery replenishment orders when the total value of all subscribed items exceeds $25 after discount is applied. Shipping surcharge may apply if delivered to Alaska or Hawaii.
      One-time coupon discounts don’t carry over to recurring orders.If a coupon offer is applied to purchase of multiple items (i.e. “Buy One, Get One 50% Off, Buy 2, Get 1 Free, etc...) and you select Auto Delivery, all items will be added as recurring orders.
      You may return any item purchased from the Vitamin Shoppe for any reason within thirty (30) days of purchase. For online and catalog orders, the product ship date is the date of purchase. Refunds for unopened items will be issued via your original form of payment with one exception. Online orders paid for with PayPal and returned to a Vitamin Shoppe retail store will be refunded via merchandise credit.