Reduced Glutathione

Glutathione protects cells from the free radicals produced through oxidation. It can only do this by remaining in its naturally reduced state so that it is readily available to neutralize free radicals by bonding with them. As GSH bonds it converts to its oxidized form, called glutathione disulfide. Then an enzyme---glutathione reductase---reverts it back to its reduced state. The ratio of reduced GSH to oxidized GSH within the cells can be used to measure cellular toxicity. In healthy cells, 90 percent of the GSH should be in its reduced form.

Supplements

Since glutathione is so important to maintaining cell health it would seem logical to take supplements to ensure an adequate supply. However, researchers have found that glutathione is not absorbed well through the digestive system. GSH is produced naturally in the body from cysteine, glutamate and glycine. Since cysteine is the building block that enables its participation in redox reactions, the focus for supplements is on using cysteine to ensure the body has sufficient quantities to produce GSH.

Significance

Without this powerful antioxidant, the cells in the body would not be protected from oxidative injury. They would be damaged and killed, setting off an inflammation response. GSH also has several other roles. In the liver it helps to transport amino acids across cell membranes so that they can be converted into proteins. It is also essential for the detoxification of acetaminophen, so if the supply of GSH becomes too low, liver toxicity results.

  I have wondered about that also since their previous version of this product did not have 'reduced' in it...but I can tell you that the reduced version is also effective. I can actually see the positive changes it makes for me. I take it daily!

  Reduced is a term used to describe the type of Glutathione. Reduced Glutathione and L-Glutathione are actually the same and it is this form used in oral supplements. Your body uses the reduced form as an antioxidant.

  Don't know what is meant by reduced..But glutathione is
is used to monetize the metals in your body through
ingestion.

  Alzheimers is a high suspect result of a build up of heavy metals & toxic chemicals in the brain. Eliminate all metals i.e. aluminum found in deoderant, cook-ware etc. Eliminate packaged food that contain preservatives. Eat organic whenever possible. Remove amalgam tooth fillings. Chelation therapy may be in order to help remove the metals from the body. The glutathione in my opinion is not going to help with inflammation but will help with the detox process. Hope this helps.

  Honestly, I don't know. I have a lot of joint inflammation problems, and I am taking this supplement in the hope that it will help. The antioxidant properties of glutathione may help with reducing the concentration of free radicals.

Hope he gets better!

  I believe this product reduces free radicals and in so doing reduces the adverse effects of hepatotoxic agents on the liver.

  I take this along with bromalain and curcumin. The three together have reduced inflammation for me.