Primal Defense ULTRA – Ultimate Probiotic Formula – 15 Billion CFU (90 Vegetarian Capsules)

Primal Defense ULTRA – Ultimate Probiotic Formula – 15 Billion CFU (90 Vegetarian Capsules)

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Product Info

About This Product

  • Primal Defense Ultra probiotic supplement contains Lactobaccilus acidophilus, Bifidobacteria, and other strains to maximize the benefits of a healthy diet, boost nutrient absorption, relieve constipation and support digestive health
  • The only shelf stable daily probiotic powder formula containing a unique whole food blend with Homeostatic Soil Organisms (HSO)
  • This dietary supplement has 15 billion CFU and 13 hardy beneficial strains for immune system health
  • This bifidobacterium probiotic is whole food, gluten free, vegetarian probiotics supplement for a balanced, health internal environment
  • These probiotics for constipation promote regular, healthy and comfortable bowel movements

It combines the benefits of 15 billion CFU and 13 robust strains, including the renowned lactobacillus acidophilus. The inclusion of SBO probiotics, such as Homeostatic Soil Organisms. Designed to fit into your regimen of supplements for women and men, it acts as probiotics for men and women that promote digestive health by supporting a balanced internal environment.† By supporting regular digestive function and immune resilience, Primal Defense Ultra is a great choice for maintaining your body's natural defenses.† Contains Bacillus subtilis to support healthy lactic acid bacteria (Bifidobacterium and/or Lactobacillus) count and healthy pH levels in the gut. The Saccharomyces boulardii in Primal Defense Ultra nourishes intestinal mucosa cells to support the normal barrier function of the intestinal epithelium, the front line for the body's defense system.†

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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Directions

Adults begin with 1 capsule per day with 8oz. of water or juice and gradually increase to 1 capsule 3 times per day. Best taken on an empty stomach.

Warning

As with any dietary supplement consult your healthcare practitioner before using this product, especially if you are pregnant, nursing or under medical supervision. Warning: if you are currently undergoing HIV treatment, chemotherapy, or allograft therapy, do not use before consulting your physician. Do not use if safety seal is broken or missing. Store in a cool dry place. These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Supplement Facts

Serving Size: 1 Capsule
Number of Servings: 90 Servings
Amount Per Serving
% Daily Value
IRON FROM IONIC PLANT BASED MINERALS   
10%
HSO PROBIOTIC BLEND  - (5 BILLION CFU)
N/A*
SACCHAROMYCES BOULARDII   
N/A*
BARLEY GRASS   
N/A*
OAT GRASS   
N/A*
LACTOBACILLUS PLANTARUM   
N/A*
BACILLUS SUBTILIS   
N/A*
Lactobacillus Paracasei   
N/A*
Bifidobacterium Longum   
N/A*
Bifidobacterium Bifidum   
N/A*
BIFIDOBACTERIUM BREVE   
N/A*
Bifidobacterium Lactis   
N/A*
Lactobacillus Acidophilus   
N/A*
LACTOBACILLUS CASEI   
N/A*
Lactobacillus Rhamnosus   
N/A*
Lactobacillus Salivarius   
N/A*
LACTOBACILLUS BREVIS   
N/A*
IONIC PLANT BASED MINERALS   
N/A*

Other Ingredients:

Vegetable cellulose (capsule), organic rice (hull)

Specifications

Brand:
Garden of Life
Form:
Capsules
Strength:
15 BILLION
Serving Size:
1 Capsule
Number of Servings:
90 Servings
Price per Serving:
($0.56 / serving)
Product Weight:
9  OZ
Specialty Diets:
Gluten Free ,  Vegetarian ,  Dairy Free
Item # :
GU-1062 / 1642321

Product Reviews

101 Ratings
4.7out of 5 stars
101 Ratings

Rated 5 stars by 83% of reviewers

Rated 4 stars by 9% of reviewers

Rated 3 stars by 3% of reviewers

Rated 2 stars by 4% of reviewers

Rated 1 star by 1% of reviewers

1-10 of 101 Reviews
Feb 10, 2026
Rated 3 out of 5
Review Garden of life prebiotic Ultra.
I would rather have the original Garden of Life probiotics.
Location
Kasilof, AK, US
Gender
Female
Age Range
65+
Would you recommend?:Yes
Purchased on Jan 26, 2026
Sep 6, 2024
Rated 5 out of 5
Excellent results
Hi, I tried this as recommended by a PA when I was suffering from bloating and heartburn and it did the trick. I use the less expensive 416mg or 5 Billion CFU version and it works fine for me just taking 2 per day (AM and PM) versus the three recommended. VS continues to label all these 15Billion CFU for some reason, but the less expensive one is definitely labeled 416mg / 5 billion.
Location
San Rafael, CA
Gender
Male
Age Range
65+
Would you recommend?:Yes
Jun 24, 2023
Rated 5 out of 5
Excellent product
Excellent product
Location
Ontario, CA, US
Gender
Male
Age Range
45-54
Would you recommend?:Yes
Purchased on Aug 3, 2020
Feb 3, 2023
Rated 5 out of 5
Great Product!!
Best I have used!
Location
Boise, ID, US
Gender
Female
Age Range
55-64
Would you recommend?:Yes
Purchased on Apr 26, 2016
Dec 6, 2022
Rated 5 out of 5
Can?t live without
I started using these when I was in my late 20?s with digestive issues. I am now 45. I took a break 2 years ago thinking I could do without for about a year trying to save money thinking maybe they weren?t worth it. Boy was I wrong. These are worth every penny. Can?t put a price tag on being regular!
Location
OR, US
Gender
Female
Age Range
45-54
Would you recommend?:Yes
Purchased on Sep 19, 2014
Jul 30, 2021
Rated 5 out of 5
very effective
these are very good at maintaining overall gut balance
Location
paris, TN, US
Gender
Male
Would you recommend?:Yes
Purchased on Jun 28, 2021
Apr 22, 2021
Rated 5 out of 5
Best product ever
My favorite product cannot live without it!
Location
Waxhaw, NC, US
Gender
Female
Age Range
55-64
Would you recommend?:Yes
Purchased on Mar 21, 2021
Apr 14, 2021
Rated 2 out of 5
Didn't work for me
I have IBS-C and after reading the great reviews, decided to try this for my chronic constipation. It did not work. In fact it made the constipation worse. Too bad - I was so hoping it would provide me with relief. I really like Garden of Life products.
Location
Sarasota, FL, US
Gender
Female
Age Range
65+
Would you recommend?:No
Purchased on Mar 6, 2021
Feb 21, 2021
Rated 5 out of 5
Excellent
I have been using Primal Defense Ultra for several years now. I wouldn't be without it. It definitely assists me with my digestive issues. I highly recommend it. Garden of Life is an excellent company and has expanded over the years...very trustworthy.
Location
Celina, OH, US
Purchased on Jan 21, 2021
Nov 20, 2020
Rated 5 out of 5
Good probiotic
I have tried a few others. I feel like Primal Defense Ultra Probiotic is definitely helping keep any stomach issues I had, away. Highly recommend!
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

Q&A

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Start typing and see existing answers.
15 Questions
Why did you choose this?

Not synthetic. No GI upset. Doesn’t have to be refrigerated. Reputable company.

Help immune system

Quality

Works well. Have used it several years

Is there an expiration date of use by date?
Does this product contain broccoli?

  The write up says it is gluten free but I wonder since barley contains gluten?

  No, I don't see it on the label.

  Is this product gluten free?

  No

  Broccoli is not in the list of ingredients

Vote for the best answer above!

HOW CAN I BEST SEE A DIFFERENCE IN MY PERSONA....?
Is this gluten free?

  vegetarian and gluten free are not the same. gluten free is as stated. etc. thanks though

  Not sure if "Ultra" is truly gluten-free, but the regular "Primal Defense" is gluten-free and states it is "Gluten-free" on the label. I'm on a strict gluten-free diet due to Celiac's and the regular Primal Defense has posed not problems to my condition.-Rena

Thanks so much!

  The capsules are vegetarian, so I can only assume that they are gluten free.Hope this helps.

  Yes, the label on the bottle states "gluten free."

Thanks!

Vote for the best answer above!

how many do you take per day?

  To get the 15 bn you have to take three a day, each giving 5 bn. I take one in the morning and one at night and am fine with it. Actually wouldn't recommend taking more than one a day until your body acclimates. I don't swear by much but think this is an excellent all-around health item. Healthy gut = healthy person.

  3 to 4, one with every meal. They work well but I've switched brands, InnovicLabs multi-strain probiotic. I now only take 2 a day, 1 with breakfast and 1 with dinner and seem to do much better.Garden of Life is a good brand, which I took for many years. I just decided to try something different and it worked.

  I take one every morning on an empty stomach. If I'm having stomach problems, I do up to three per day (before meals).

  I take two a day--one in the morning, one at night. Have been taking them for years and they do seem to help.L

  only one per day. If I feel a cold coming on or am traveling or have been on antibiotics I will take two.

  I only take 1/day now and it seems to do the trick. When I was in an acute stage, I did 2/day.

  One, it is a great probiotic

  I take three tablets daily.

Vote for the best answer above!

how do I store it.....?

  I store mine in the refrigerator. I think it was one of the best health decisions I ever made, to take these probiotics. Hope you find the same.

  I keep it in the refrigerator, but that's not necessary. The label advises keeping it in a cool, dry place.

  IStore it in my dining room, if stomach acid won't destroy it, temperature will not.

  For longer freshness, i keep unopened bottles in fridge.

  Once I opened it, I kept it in the fridge.

  I keep mine in the fridge

Vote for the best answer above!

Does this product need to be refrigerated?

  Hi, this is Julie H, the person who posted the question. Thank you all for your responses. I decided to also contact Garden of Life customer support and here is their response: "Thank you for your email and interest in Garden of Life's products. The probiotics used in our Primal Defense formulas do not need refrigeration because they remain dormant in a dry state and only activate when they become moist. This process begins when they are ingested and so activation will begin in the gut. If the products are refrigerated once opened the probiotics may become moist, and possibly activate before they are ingested. This goes for all of our Primal Defense formulas. Please store the Primal Defense in a cool dry place such as a kitchen cabinet/pantry."

  when I purchase this at my local health food stores, it is always in a cooler shelving unit, but not a actual refrigerator, but I do keep mine in my refrigerator at home. I always think any live probiotic should be refrigerated. But let be know if you know something different.Karen

  The product label says to store in a cool dry place so you do not have to refrigerate this product. I usually store it in my pantry.

  It is better if refrigerated.

Vote for the best answer above!

Is this safe to use everyday?

  Like with any probiotic, use and adjust based on your condition. Too much can cause bloating, so you need to give your system time to adjust. Garden of life offers great quality, but like with any supplement, always try and see how you feel. You may decide to take it every day or once a week. Remember that everyone's digestive system is unique.

  Yes I take it everyday for the past couple of years !

  Yes

Vote for the best answer above!

Does this probiotic have inulin or milk product?

  The capsules are vegetarian. I do not see inulin anywhere on the label, but I am not familiar with it. You may want to Google "Garden of Life" to make sure.

I just saw the other reply about it being cultured in dairy. Yes, it is.

  Cultured in dairy

Vote for the best answer above!

can a 12 year old take these?

  They are the strongest. I see no reason why not. Not sure why you want a child to take but if not a medical type issue and just general health save money and get the regular ones.

  best to check with your doctor/naturopath

Vote for the best answer above!

Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

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