Berberine HCl - Supports Cardiovascular & Immune Health - 500 MG (120 Vegetarian Capsules)

Berberine HCl - Supports Cardiovascular & Immune Health - 500 MG (120 Vegetarian Capsules)

Open modal
Open modal
Delivery Options

Open modal

About This Product

  • Provides blood sugar support
  • Supports cardiovascular health
  • Promotes natural immunity
  • Suitable for everyday wellness seekers
  • Free of gluten, dairy, soy, nuts, sugar, salt, animal derivatives, and artificial colors or flavors

Berberine HCl is a naturally occurring alkaloid found in an array of plants including phellodendron chinense, goldenseal, tree turmeric, and barberry. Berberine HCl plays an essential role in supporting healthy blood sugar levels, natural immunity, and cardiovascular function.

Formulated to help you achieve your wellness goals, The Vitamin Shoppe® brand Berberine HCl capsules are a convenient 3-in-1 solution for immune, cardiovascular, and blood sugar health.

Read More

Directions

Take one (1) vegetable capsule daily, with a meal.

Warning

Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions. Store in a cool, dry place. Keep out of reach of children. Tamper evident. Do not use if outer seal is broken or missing.

Read More
Serving Size: 1 Capsule
Number of Servings: 120 Servings
Amount Per Serving
% Daily Value
BERBERINE HCL   
N/A*

Other Ingredients:

Vegetable Capsule (hypromelliose), Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Stearic Acid.

Brand:
The Vitamin Shoppe
Form:
Vegetarian Capsules
Strength:
500 MG
Serving Size:
1 Capsule
Number of Servings:
120 Servings
Price per Serving:
($0.37 / serving)
Product Weight:
5  OZ
Allergens:
Egg Free, Fish Free, Milk Free, Peanut Free, Shellfish Free, Soy Free, Tree Nut Free, Wheat Free
Specialty Diets:
Gluten Free ,  Dairy Free
Item # :
VS-3919 / 2187854
29 Ratings
4.3out of 5 stars
29 Ratings

Rated 5 stars by 72% of reviewers

Rated 4 stars by 3% of reviewers

Rated 3 stars by 14% of reviewers

Rated 2 stars by 7% of reviewers

Rated 1 star by 3% of reviewers

Would you recommend?
1-10 of 29 Reviews
Aug 12, 2026
Rated 5 out of 5
Good Choice!
I really like this supplement. I've been taking it for a couple of weeks and it's definitely helping me. Glad I found Vitamin Shoppe!
Location
Kennesaw, GA, US
Gender
Female
Age Range
55-64
Would you recommend?:Yes
Purchased on Jul 25, 2026
Aug 5, 2026
Rated 5 out of 5
great product
great product
Location
Hsjsosm, CT, US
Gender
Female
Age Range
25-34
Would you recommend?:Yes
Mar 20, 2026
Rated 5 out of 5
Berberine HCL
My husband has been taking Berberine for about 9 mths. It has helped level his A1C. Even his dr. has been surprised.
Location
Metairie, LA, US
Purchased on Feb 26, 2026
Sep 29, 2025
Rated 5 out of 5
Will buy more
Definitely has helped with my appetite. Not quite 30 days in but it seems to be helping with my blood sugar too.
Location
Cincinnati, OH, US
Gender
Female
Age Range
45-54
Would you recommend?:Yes
Purchased on Sep 2, 2025
Aug 6, 2025
Rated 3 out of 5
I can't tell if it worked as I tried it for several months with no real change.
This Berberine did not give me a headache or anything. I can't tell if it worked as I tried it for several months with no real change. Maybe I need to take it for longer.

I workout 4-5 times a week, eat very healthy, track my food so not sure if it was worth it.
Location
Fresno, CA, US
Gender
Female
Age Range
45-54
Purchased on Jan 21, 2019
Aug 2, 2025
Rated 3 out of 5
Where is it
My purchase has not arrived yet
Location
Owatonna, MN, US
Gender
Male
Age Range
65+
Would you recommend?:No
Purchased on Jul 18, 2025
Jun 30, 2025
Rated 5 out of 5
Awesome product
Awesome product
Location
SAN DIEGO, US
Gender
Female
Age Range
25-34
Would you recommend?:Yes
Purchased on May 16, 2025
Jan 27, 2025
Rated 5 out of 5
Worked for me
I believe this product helped me lower my A1C. I made some changes with diet and exercise that helped lower it some, but I saw an even greater improvement after taking this product. Additionally, I have not experienced any stomach or gastrointestinal issues while taking it, and I have done up to three a day with no problem.
Location
MD, US
Gender
Female
Age Range
55-64
Would you recommend?:Yes
Purchased on Jun 6, 2023
Dec 6, 2024
Rated 5 out of 5
Great for lowering cholesterol
I have tried many things to help lower my cholesterol, refusing to take statins. I have been taking Cholestoff for years and although it has helped, my numbers were still high. I've been taking this berberine hcl with citrus bergamot for the last several months. My last blood draw showed everything was perfect, even my cholesterol!!! This is a game changer for me!
Location
Knoxville, TN, US
Gender
Female
Age Range
55-64
Would you recommend?:Yes
Purchased on Sep 18, 2024
Jun 1, 2024
Rated 5 out of 5
Berberine HCI 500 MG
I started taking Berberine 4/28/24. I was 160 pounds. Today is 6/1/24 and I weigh 151. Taking the Berberine has helped suppress my appetite along with eating healthy foods and exercising. I have one more bottle since it was BOGI half off. I am excited to see how much I will lose in the next 30 days. Stay tuned!!!
Location
Cedar Hill, TX, US
Gender
Female
Age Range
45-54
Would you recommend?:Yes
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

We'll email them your question, then email you their replies.

Have a question? Ask owners.Have a question about this? Ask people who own it.
Start typing and see existing answers.
7 Questions
Why did you choose this?

always use

this is for Pre diabetes and Type 2 diabetes

Works

it works

How many capsules of Berberine 500mg 
should I take?

Best Answer:  Please follow the directions for best results, which states to take one daily.

3rd party verified?

Best Answer:  No idea

Can I take more than one a day?

Best Answer:  Yes-

I take two before each meal for blood sugar control.

Can’t swallow large pills, can I open these and sprinkle in food???

Best Answer:  Yes, this item would be a capsule which contains a powdered supplement inside. It can be opened and mixed with food if needed.

What is the Pureness of the berberine?
Does this help with sugar cravings?
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

 

FREE STANDARD SHIPPING on orders of $45 or more

How to get FREE Standard Shipping:

  1. Ship to an address within the United States (including U.S. territories)
  2. Place your online order of $45 or more* - after promotions and before tax are applied
  3. Use "Standard" shipping option at checkout

Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

 

*Excludes all orders placed on major US holidays (Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day and New Year's Day).

 

Orders for states outside of the continental U.S. (including those of $45 or more) may be subject to a delivery surcharge. This will be noted in the order summary based on your shipping address at checkout.

back to top

About The Vitamin Shoppe

Featuring a wide range of quality vitamins, minerals, and supplements at everyday low prices, every formula is verified for ingredient potency and purity—to help you become a better you.

Shop The Vitamin Shoppe
The Vitamin Shoppe logo

Experts Break it Down


The Hype Is Real With Berberine: 3 Science-Backed Benefits

The Hype Is Real With Berberine: 3 Science-Backed Benefits

Berberine might just be one of the natural supplement world’s best-kept secrets due to its broad range of science-backed, health-boosting qualities. Read on for more about this powerful plant extract.

How To Get The Best Results From Your Berberine Supplements

How To Get The Best Results From Your Berberine Supplements

Berberine has become a compelling choice for just about anyone seeking to enhance their health. Read on to learn more about berberine’s benefits, as well as how to maximize your results.

12 Things To Do If Your Blood Sugar Tests Come Back Abnormal

12 Things To Do If Your Blood Sugar Tests Come Back Abnormal

Looking to stabilize your blood sugar levels? Here’s why doing so is crucial, plus 12 immediate changes you can make to your daily routine.

7 Things That Throw Your Blood Sugar Off Balance

7 Things That Throw Your Blood Sugar Off Balance

Various lifestyle choices and environmental influences can unexpectedly throw your sugars out of whack. Fortunately, most of these factors are largely within your control.

Looking For More
Related Products
  • Rainbow Light Nutritional Systems
    Naturally Derived Berbine - 1,00o mg - Ceylon
    Rainbow Light Berberine Complex features a blend of berberine sourced from four potent herbs, combined with Ceylon Cinnamon and Chromium. This comprehensive formula supports your wellness goals, including healthy sugar metabolism.
     
    $29.99
  • Force Factor
    Ultra Berberine - Glucose & Metabolism Formula for
    Berberine is one of nature’s most versatile plant-based extracts. Scientifically studied across the globe to support a variety of health factors, it’s become a popular and powerful way to support blood sugar levels and glucose metabolism. Ultra Berberine delivers a 500mg dose of this potent compound in every daily serving. It also includes added chromium, a mineral that supports nutrient metabolism, and cinnamon bark extract to support insulin sensitivity. Just two capsules per day is all it takes to support your blood sugar, metabolism, and overall daily wellness.
    Rated 5.0 stars out of 5 stars, From 86 customer reviews 
    $24.99
  • Force Factor
    Ultra Berberine for Blood Sugar Support - Glucovantage
    Berberine is a popular and powerful way to support healthy blood sugar levels, glucose metabolism, and weight loss. Ultra Berberine Enhanced Absorption takes this potent plant-based extract to the next level. It’s powered by Glucovantage Dihydroberberine, providing 5x better absorption and lasting 2x longer than traditional berberine. It’s also gentler on the stomach, so you won’t have to worry about digestive discomfort. Fortified with Chromax chromium, ceylon cinnamon, and inositol to maximize insulin sensitivity, control appetite, promote fat loss, and prevent weight gain, Ultra Berberine Enhanced Absorption is an effective way to improve the way you look and feel.
    Rated 5.0 stars out of 5 stars, From 1 customer reviews 
    $29.99
  • Vthrive
    Advanced Blood Sugar Support - Antioxidant & Nutrient
    • Provides blood sugar support
    • Promotes nutrient metabolism
    • Provides antioxidant support
    • Non-GMO
    • Free of gluten and soy

    Fend off blood sugar spikes and crashes with Advanced Blood Sugar Support from Vthrive™ The Vitamin Shoppe®. Formulated with 500mcg of chromium per serving, these vegetarian capsules promote nutrient metabolism to help you feel balanced and energized.

    You need the best to achieve your best. That's why these clean Vthrive The Vitamin Shoppe supplements are non-GMO and free of artificial additives, magnesium stearate, stearic acid, and titanium dioxide.

    Frequently Asked Questions

    What's chromium?

    Chromium is an essential trace mineral that supports insulin function and glucose metabolism.

    Rated 5.0 stars out of 5 stars, From 35 customer reviews 
    $19.99

Page loadingLOADING...