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Up to $20 Off $100 Plus Free Shipping. Online only. | Code: SNAPITUP

Cleanse & Detox

Feeling sluggish or out of sync? A cleanse and detox routine may help support your body’s natural elimination processes and give you a fresh start. At The Vitamin Shoppe, we offer a wide range of cleanse and detox supplements—from full-body options to targeted formulas for the liver, kidneys, and digestive system.

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digestive health essentials

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Mag O7 Ultimate Oxygenating Digestive System Cleanser (180 Vegetable Capsules)
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$41.99
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Liver Health Support Formula (120 Vegetarian Capsules)
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$54.99
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Liver Cleanse - Antioxidant to Support Liver Health (60 Vegetable Capsules)
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$21.99
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Kidney - Healthy Kidney Support (135 Capsules)
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$54.99
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The Cleaner - 14-Day Women's Formula - Ultimate Body Detox (104 Capsules)
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$34.99
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Mega Clean Herbal Liquid Cleanse - Tropical Fruit (32 Fluid Ounces)
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$35.19
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The Cleaner - 7-Day Women's Formula - Ultimate Body Detox (52 Capsules)
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$19.99
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Super Colon Cleanse with Psyllium Husks, Senna Leaf, Acidophilus & Papaya (240 Capsules)
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$31.99
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Mag O7 Ultimate Oxygenating Digestive System Cleanser (90 Vegetable Capsules)
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$27.99
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Liver Support – Herbal Formula with Milk Thistle & Oregon Grape (90 Vegetarian Capsules)
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$21.99
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Cleanse More Herbal Formula with Magnesium (100 Vegetable Capsules)
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$37.99
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Liver Care - Healthy Liver Support & Detox (180 Vegetarian Capsules)
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$44.20
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Puri-T for Liver Support with Milk Thistle & NAC (60 Vegetarian Capsules)
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$30.99
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Milk Thistle for Liver Health - Full Spectrum Extract & Whole Seed (90 Capsules)
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$20.99
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The Cleaner - 14-Day Men's Formula - Ultimate Body Detox (104 Capsules)
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$34.99
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Liver Detox with Turmeric Root, Milk Thistle, NAC & Alpha Lipoic Acid - 620 MG (60 Capsules)
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$32.99
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Super Colon Cleanse with Psyllium Husks, Senna Leaf, Acidophilus & Papaya (120 Capsules)
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$21.99
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Liver Cleanse for Healthy Liver Function Support with Milk Thistle (60 Vegan Capsules)
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$31.49
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Liver Support with Milk Thistle - 70 MG - 80% Silymarin (100 Tablets)
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$24.99
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Super Colon Cleanse with Psyllium Husks, Senna Leaf, Acidophilus & Papaya (68 Servings)
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$23.99
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Milk Thistle Liver Detox with Dandelion, Artichoke & Beet Green (60 Softgels)
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$29.99
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The Cleaner - 7-Day Men's Formula - Ultimate Body Detox (52 Capsules)
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$19.99
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Original Colon Cleanse - Natural Daily Fiber, Psyllium Husks Powder (194 Servings)
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$67.99
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Para End 15 Day Microbial Cleanse & Detox Program (90 Vegetable Capsules)
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$34.99
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Kidney Cleanse with Cranberry, Buchu Leaf, Turmeric & CoQ-10 - 550 MG (60 Capsules)
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$27.99
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Men's 7 Day Cleanse - Detox Formula with Probiotics & Electrolytes (52 Vegetable Capsules)
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$18.99
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DeTox Tea - Caffeine Free (16 Tea Bags)
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$5.99
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Milk Thistle for Liver Health Support - 300 MG (100 Capsules)
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$21.99
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LiverCare - Healthy Liver Support & Detox (90 Vegetarian Capsules)
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$27.62
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Milk Thistle - Full Potency Herb (100 Vegetarian Capsules)
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$25.99
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Liver Blend SP-13 - Dandelion-Milk Thistle - 475 MG (100 Capsules)
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$12.99
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Ultimate Cleanse - 2 Part Total Body Program (240 Tablets)
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$41.99
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Organic Triphala - Digestion & Colon Cleanse (90 Vegetarian Capsules)
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$20.99
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Related Searches

What is a cleanse and detox?

A cleanse and detox typically refers to a regimen aimed at supporting the body’s natural ability to eliminate waste and toxins through organs like the liver, kidneys, and colon. While your body already has built-in detoxification systems, certain supplements and herbs may help support these processes—especially when paired with a healthy diet and lifestyle.

Whether you're looking for a natural cleanse and detox after a period of indulgence or want to maintain regularity and organ health, our selection includes capsules, liquids, teas, powders, and more to help you feel refreshed and rebalanced.

What are the potential benefits of a cleanse or detox?

Goals of a detox and cleanse may include:

  • Supporting liver and kidney function
  • Promoting digestive regularity
  • Encouraging healthy skin and energy levels
  • Supporting immune health and metabolic balance

Some formulas target specific organs or systems of the body, so the potential benefits can vary by product.

Targeted detox & cleanse supplements

The Vitamin Shoppe carries top body cleanse options, from complete regimens to natural detox support supplements. Explore a variety of cleanse and detox body solutions tailored to your needs.

  • Total-body detox: Convenient all-in-one programs ranging from 3-day resets to month-long cleanses. These kits often include herbal blends designed to gently support elimination and organ health.
  • Liver cleanse and detox: Supplements that may support liver function, one of the body’s primary detox organs.
  • Kidney cleanse and detox: Formulas designed to promote urinary tract health and help the kidneys filter waste.
  • Colon cleanse and detox: Products that may support digestive regularity and intestinal health.
  • Detox teas: Herbal blends that may support kidney, liver, and blood health while offering a soothing daily ritual.

What are the best cleanse detox brands?

The Vitamin Shoppe carries many name brands, including these top labels: The Vitamin Shoppe, Detoxify, Herbal Clean, Health Plus, and Renew Life.

Shop Cleanse & Detox at The Vitamin Shoppe

Ready to reset and recharge? Whether you're starting a full body cleanse and detox, liver and kidney cleanse detox, or simply want to support your body's natural processes, we have the products to help you feel your best. Browse our full selection online or visit your local Vitamin Shoppe store for everything you need to support your wellness journey.

Find Cleanse & Detox at The Vitamin Shoppe Store Near You

There are over 600 The Vitamin Shoppe® stores across the US, so it's very likely you can pop in and find Cleanse & Detox locally. Check out our store locator to find a shoppe near you. Don’t forget about saving 10% on every subscription with Auto Delivery to help you stay on the path and never miss a thing, plus: Free Shipping!* You define what better looks (and feels) like—Count on us to help you get there.


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  • FREE for Orders over $35

    Orders under $35, domestic shipping is only $6.99. Find more at our Shipping Policy page.

    • Return Policy for Items Purchased Online

    Shop with confidence with our Easy Returns Policy. Customers may return any opened or unopened merchandise purchased from any Vitamin Shoppe channel to any Vitamin Shoppe store within 30 days. Find more at our full Returns Policy page.

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