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SAM-e - Enteric Coated - Mood, Joint, & Liver Support - 400 MG (60 Tablets)

SAM-e - Enteric Coated - Mood, Joint, & Liver Support - 400 MG (60 Tablets)

$49.99
($0.83/serving)

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SAM-e - Enteric Coated - Mood, Joint, & Liver Support - 400 MG (60 Tablets)

Rated 4.9 out of 5
16 Reviews9 Questions251 Answers
Gluten FreeDairy FreeSugar FreeSoy FreeWheat Free
$49.99
($0.83/serving)

EXCLUSIVE

ONLY AT THE VITAMIN SHOPPE

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Product Info

About This Product

  • Provides mood support
  • Supports joint and liver health
  • Free of gluten, dairy, soy, and nuts

The Vitamin Shoppe® brand SAM-e tablets are perfect for when your mood needs a little support. S-adenosylmethionine (SAM-e) is a compound involved in the production of serotonin and dopamine—AKA our feel-good hormones. Studies show that SAM-e can also promote joint and liver health.

Add this supplement to your routine to support a positive mood, flexible joints, and a healthy liver.

Frequently Asked Questions

What is an enteric coating?

An enteric coating protects the supplement from the harsh, acidic environment of the stomach. It allows the supplement to release once it passes through the stomach for optimal absorption.

Read More

Directions

As a dietary supplement, take one (1) tablet per day on an empty stomach, or as directed by your physician.

Warning

Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions. KEEP OUT OF REACH OF CHILDREN.

Read More

Supplement Facts

Serving Size: 1 Tablet
Number of Servings: 60 Servings
Amount Per Serving
% Daily Value
S-ADENOSYL-L-METHIONINE  - (SAM-E) (AS S-ADENOSYL-L-METHIONINE TOSYLATE DISULFATE)
N/A*

Other Ingredients:

Cellulose, silica, magnesium stearate, riboflavin, ethyl cellulose, oleic acid, medium chain triglycerides, sodium alginate, modified cellulose, triacetin, calcium carbonate, ammonium hydroxide.

Does Not Contain:

Preservative Free, Free of Artificial Flavors, Free of Animal Derivatives

Specifications

Brand:
The Vitamin Shoppe
Form:
Tablet(s)
Strength:
400 MG
Serving Size:
1 Tablet
Number of Servings:
60 Servings
Price per Serving:
($0.83 / serving)
Product Weight:
8  OZ
Allergens:
Fish Free, Soy Free, Wheat Free
Specialty Diets:
Gluten Free ,  Dairy Free ,  Sugar Free ,  Yeast Free
Item # :
VS-2659 / 1721133

Product Reviews
   (16)

16 Ratings
4.9out of 5 stars
16 Ratings

Rated 5 stars by 88% of reviewers

Rated 4 stars by 12% of reviewers

Rated 3 stars by 0% of reviewers

Rated 2 stars by 0% of reviewers

Rated 1 star by 0% of reviewers

1-10 of 16 Reviews
Jun 29, 2023
Rated 5 out of 5
works well
no digestive issues caused by additives
SerenaVerified Purchaser
Would you recommend?:Yes
Purchased on May 14, 2021
Was this helpful?
Sep 17, 2021
Rated 5 out of 5
Only brands that works!
I?ve tried many other brands and Vitamin Shoppe brand is hands down the best. Works on mood stabilization and it a staple for me!
SHARIE BVerified Purchaser
Location
Plainfield, IN, US
Gender
Female
Age Range
18-24
Would you recommend?:Yes
Purchased on Jun 9, 2021
Was this helpful?
Jun 7, 2021
Rated 5 out of 5
Sam-e for my dog
I?m using this for my dog which has Valley Fever. He is currently on Fluconazole, Olive Leaf, Milk Thistle and Sam-e. He is doing much better with the regimen he is on.
TAMARA NVerified Purchaser
Location
Newbury Park, CA, US
Gender
Female
Age Range
55-64
Would you recommend?:Yes
Purchased on Apr 27, 2021
Was this helpful?
Aug 17, 2020
Rated 5 out of 5
Sam-e
Works as advertised and expected. Easy to take for me.
Brad JVerified Purchaser
Location
Queen Creek, AZ, US
Gender
Male
Age Range
55-64
Would you recommend?:Yes
Purchased on Jul 17, 2020
Was this helpful?
Jul 13, 2018
Rated 5 out of 5
SAM-e
I've been using SAM-e for several months and I truly believe it has helped me with my overall emotional well being
DEBBY BVerified Purchaser
Location
Beachwood, OH, US
Gender
Female
Age Range
65+
Would you recommend?:Yes
Purchased on Jun 28, 2018
Was this helpful?
Nov 13, 2015
Rated 4 out of 5
Sam E is amazing aa a mood enhancer!
Price a nd size of pills are both perfect.
Creacher
Location
Miami, Fla.
Would you recommend?:Yes
Was this helpful?
Feb 20, 2014
Rated 5 out of 5
Love It!
This product helps with my fibromyalgia pain and stiffness. It's easy to take and produces results.
Dee
Location
Acworth, GA
Would you recommend?:Yes
Was this helpful?
Dec 26, 2013
Rated 5 out of 5
Too high a price?
I could feel the difference when I did or didn't takemy Sam-E but in the store I was shocked at the price.I ran all over town when it was on a rare sale. The V-shop brand is affordable enough I can up my dose till the days lengthen again. No difference in quality.
Menopaused & SADD
Location
Greenville, SC
Would you recommend?:Yes
Was this helpful?
Nov 7, 2013
Rated 4 out of 5
SAMe
use as a nutritional suppliment
Jeff
Location
Falls Church, VA
Would you recommend?:Yes
Was this helpful?
Aug 28, 2013
Rated 5 out of 5
I hope it works!
I began taking this product over 15 years ago due to my inherited osteoarthritis and the pain it caused me on long runs. The mood improving effect may be responsible for most benefits, but the end result is that I could run and work out. I noticed the difference in my endurance and enthusiasm during times when I was without this supplement due to not being able to obtain it. I can't attribute any earth-shaking effects to this supplement, but it has been useful as a part of my total diet. during…
Road Doctor
Location
Maryland's Eastern Shore
Would you recommend?:Yes
Was this helpful?
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

Q&A

We'll email them your question, then email you their replies.

Have a question? Ask owners.Have a question about this? Ask people who own it.
Start typing and see existing answers.
9 Questions
Why did you choose this?
The Vitamin ShoppeStore

Mood and joint support

Greg P

Recommended

SHARON A

Ran out

Debra B

It helps with sleep and mood

SHARON A
Does this cause stomach problems?
Cynthia B

  I've found it only causes problems (nausea) if taken with food of any substantial sort; as such, I take it directly upon waking. 20-30 minutes later food seems fine. Main issue I have noticed is a decreased appetite; not a huge one, only noticeable in a gym rat most likely! Just have it on an empty stomach and relatively early in the day and you shouldn't have any problems.

Ridge C

  I've been taking 2 a day for about a year. I have never had any stomach problems, but I do take 2 probiotics daily. I've never heard of this being a side effect though.

Kelly L.

  I have been taking it for 3 years and have noticed no stomach problems. I have a history of ulcers, and it has no effect on that at all.

Madison L

  This did not cause stomach problems for me. You are supposed to take them on an empty stomach.

Becky C

  Not in the least. I have taken Sam-E for years with zero stomach problems.

Trini E

  I haven't had any issues and I've been taking it for quite a while.

May T

  I can't say that SAMe causes stomach problems. I don't know.

Stephanie S

  Hi,Not for me.

Elzbieta J

  Not for us!

Mario C

Vote for the best answer above!

Does Vitamin Shoppe's sam-e contain mannitol (gives me stomach pain)? I didn't see it in the ingredients list but wanted to double check.
A shopper

  The only brand, until I did my source couple years ago, that no use mannitol is this brand, it's why I choose this brand.

Jacqueline L

  I am very sensitive to mannitol and have had the same problem with other brands but I have no problem with this brand.

Marli K

Vote for the best answer above!

is this free of mannitol?
A shopper

  As far as I can determine there is no mannitol. There would be no reason to include a high molecule sugar in the formulation. It is not listed on the label. Usually enteric coated tablets are protein coated to disintegrate in the duodenum.

Michael Y

  Not that I know of - best you put your question to Vitamin Shoppe - its there product.

barbara p

  That would be a question for the Vitamin Shoppe lab.........or product department.

Anne W

  I'm sorry I can't answer that. Don't know.

L H

Vote for the best answer above!

Are there any issues with SaMe interacting with other vitamins or perscription meds?
paulette a

  Ask your physician

Corinne L

Obviously the bottom line is to ask your physician. I was looking for any major issues with interaction before doing that.

paulette a

  I had no issues.

Susan C

Vote for the best answer above!

Do you become resistant to it over time?
LARRY H

  Hi LarryIn my case, no. I did realize when it came time to address other things that were making me feel unwell, however. Hormone cream, better nutrition, apple cider vinegar, and some simple yoga/exercise.. along with few mins reading C.H.Spurgeon in the morning, work for me at the moment. The Sam-E helped when I needed it, for sure.. But I have to adjust time to time what works as my body ages. Best wishes!

Kelly W

  I have been taking it for over 3 years and have not noticed any type of resistance. I'll add that I definitely notice a change in mood etc when I have been slacking off at taking it regularly, so that's important.

Madison L

  A little, but when I stopped for a period of time...I could tell the difference. It does help. I have taken it for 2 years.

Sandra B

  No, not that I am aware. I take in for a while then I stop it for a while. I believe it helps with mood more than anything.

Martin N

  Yes, it worked for me for about 1 year.

Kathryn M

Vote for the best answer above!

Does it work well with anxiety problems?
A shopper

  SAMe is known for its use in mood elevation (the opposite of depression). I can't speak to anxiety. Try L-theanine for anxiety.

Marilynn F

  Not sure--I started taking it for joint support, but I do think it has given me mood health support also.

Barb

Vote for the best answer above!

where is Sam- e manufactured?
A shopper

Best Answer:  This item is manufactured in the United States.

Daniel W.staff
I have been buying the Farrow brand. I once used nature Made and it didn't work as well. Have you tried this brand?
Ruth C

Best Answer:  I have taken it for over 3 years and really like it.

Madison L
Disclaimer:

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of the Vitamin Shoppe. Vitamin Shoppe does not verify or endorse any claims made in these reviews.Please read the full product reviews disclaimer.

Shipping Info

 

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  3. Use "Standard" shipping option at checkout

Orders will be shipped within 24 hours of order placement*, pending verification of billing information and shipping method selected. International orders and orders containing gift cards or items that are not currently in stock will be processed as quickly as possible.

 

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