Joint Health

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Blueshift Nutrition
Joint Defense Drink Mix – Blackberry Peach (10 Single-Serving Packets)
Joint Defense Drink Mix – Blackberry Peach (10
- Promotes joint health and comfort
- With clinically backed TamaFlex^® and FruiteX-B^®
- Vegan, keto friendly, and gluten free
- Zero added sugars or artificial flavors or sweeteners
- Blackberry Peach flavor
Stay active, move with confidence, and protect the joints that keep you going with Joint Defense. This ready-to-mix superblend is designed to help build and maintain healthy joint tissue while easing everyday stiffness and soreness.

Each serving features glucosamine, chondroitin, MSM, hyaluronic acid, TamaFlex, FruiteX-B, and antioxidants from turmeric and grape seed extract to promote comfort, mobility, and overall joint resilience.

Frequently Asked Questions  

What is TamaFlex? 

TamaFlex is a proprietary blend of tamarind seed and turmeric root extracts. It’s clinically shown to promote joint flexibility and reduce joint discomfort.

What is FruiteX-B? 

FruiteX-B is a patented vegan mineral complex called calcium fructoborate. It’s clinically shown to support joint comfort and mobility.

What is chondroitin?

Chondroitin is a naturally occurring compound found in joint cartilage. It’s shown to support joint flexibility and function.

What is glucosamine HCl?

Glucosamine hydrochloride (HCl) is a compound that helps maintain cartilage health, eases joint discomfort, and promotes flexibility.

What is MSM?

Methylsulfonylmethane (MSM) is an organic compound known for its ability to support joint health by promoting flexibility and circulation while reducing occasional stiffness.

What is hyaluronic acid?

Hyaluronic acid is a naturally occurring substance that lubricates the joints, supporting mobility and comfort.
$22.47
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Irwin Naturals
3-in1 Joint Formula to Rebuild, Lubricate, & Soothe (90 Liquid Softgels)
3-in1 Joint Formula to Rebuild, Lubricate, & Soothe
3-in-1 Joint Formula is a targeted formula that incorporates the latest clinical research with additional joint supporting nutrients. Clinical studies have shown that the combination of glucosamine 1500 mg per day and Chondroitin 1200 mg per day can promote joint mobility. The nutrients in this formula support healthy joints in three distinct ways:
- Rebuild: The well-known ingredients of Glucosmine and chondroitin are included in this formula at efficacious levels to help rebuild cartilage. These ingredients, along with vitamins and botanicals, promote healthy tissue, helping to maintain joint structure and mobility.
- Lubricate: Glucosamine strengths joint cartilage and Chondroitin is an important structural component of cartilage supplying joint lubrication for the cushioning effect. These two nutrients work together with MSM, an organic form of sulfur, to promote flexibility.
- Soothes: Boswellia serrata is a traditional Indian herb also known as Indian frankincense. Boswellic acids in this plant have been researched to inhibit production of leukotrienes which may lead to discomfort. Omega-3 oil works with other ingredients in this formula to lubricate tissues.
Rated 5 stars out of 5 stars, From 10 customer reviews
$39.99
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Pure Encapsulations
Ligament Restore with BioCell Collagen - Helps Maintain Healthy Joints (120 Capsules)
Ligament Restore with BioCell Collagen - Helps Maintain
Ligament Restore‡ helps support normal recovery from exercise and is best taken daily to maintain connective tissue resiliency. This supplement supports collagen formation for tendons, ligaments and joints, and it may help recovery from strains, sprains and overall wear and tear. It also supports the natural repair process of healthy connective tissue. The formula contains glucosamine, which acts as a building block for tendons, ligaments and joints. It also offers BioCell Collagen, a naturally occurring blend of hyaluronic acid, chondroitin, glucosamine and amino acids to promote cartilage synthesis and joint integrity. Collagen formation is encouraged with the amino acids lysine and proline, forming the glue that holds collagen together. The formula also includes silica and vitamin C as cofactors for connective tissue formation and repair and maintains joint comfort with devil’s claw and curcumin.
$74.99
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The Vitamin Shoppe
Ultimate Man Gold Multivitamin & Multimineral - Energy Production, Stress, Antioxidant, & Immune Support (90 Tablets)
Ultimate Man Gold Multivitamin & Multimineral - Energy
- Promotes energy production and immune health
- Offers stress and antioxidant support
- Free of gluten, dairy, soy, and nuts
Set the gold standard for your health and wellness goals with The Vitamin Shoppe^® brand Ultimate Man^® Gold Multivitamin & Multimineral tablets. Designed to fill whatever nutritional gaps that you may have, these powerful multis promote energy production and immune health while supporting healthy stress and antioxidant levels.
Rated 5 stars out of 5 stars, From 18 customer reviews
$29.99
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Why take joint supplements?

Joints are an important part of the skeletal structure because they let you move your body. From large joints like hips and knees down to smaller ones like your knuckles, joints are the connectors between bones that provide mobility throughout your body. While there are multiple types of joints, all need to be healthy to function optimally.

Besides eating a balanced diet and getting regular exercise, incorporating the right supplements into your daily health routine may help promote joint health. Learn what to look for in a supplement for joint health below so you can make joint care a part of your regular health and wellness regimen.

Ingredients commonly found in joint health supplements

Explore The Vitamin Shoppe’s inventory of supplements that contain compounds, minerals, and vitamins for joint health. You’ll find many formulas featuring one or a combination of the following popular ingredients commonly used to support healthy joints:

Glucosamine: The natural compound glucosamine is a component of cartilage, which helps cushion joints. Glucosamine supplements may support overall joint health as well as joint flexibility.
Chondroitin: This naturally occurring molecule is also a component of cartilage and connective tissues. Chondroitin helps with cartilage repair and new growth and helps connective tissues absorb fluid.
MSM: Also known as methyl-sulfonyl-methane, MSM is an organic compound that plays a role in joint and immune support. It may improve circulation and joint flexibility and help to reduce occasional pain and stiffness.
Hyaluronic acid: Present in skin cells, eyes, and the spaces around the joints, this naturally occurring carbohydrate can act as both a shock absorber and a lubricant promoting comfort and mobility.
Collagen: Collagen is a naturally produced protein (though the amount the body produces may decrease with age) that’s important for healthy joints and other body parts. It provides a supportive structure for tissues, bones, and ligaments.

Joint health vitamin and supplement blends may also contain ingredients such as calcium, vitamin D, magnesium, turmeric, and fatty acids like fish oil – each with properties that may support joint care.

Where to find supplements for joint health

Develop a joint health supplement regimen with the broad selection of products online and in-store at The Vitamin Shoppe. Find formulas to accommodate specialty diets and choose from a range of convenient forms including capsules, tablets, soft gels, powders, topical formats, and more. Shop products from The Vitamin Shoppe’s propriety line as well as other popular name brands to find the right supplement for joint health that meets your needs. Look for items with free shipping or in-store pickup, auto-delivery options, BOGO deals, and sale prices for more ways to save on your joint health supplements.

Find Joint Support at The Vitamin Shoppe Store Near You

There are more than 600 The Vitamin Shoppe® stores across the US, so it's very likely you can pop in and find Joint Support locally. Check out our store locator to find a Shoppe near you. Don’t forget—you’ll save at least 15% on every subscription with Auto Delivery, plus an addition 5% off select brands to help you stay on the path. Not only will you never miss a thing, but you’ll also get free shipping on subscription refills of $25 or more!* You define what better looks (and feels) like—Count on us to help you get there.

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Shop with confidence with our Easy Returns Policy. Customers may return any opened or unopened merchandise purchased from any Vitamin Shoppe channel to any Vitamin Shoppe store within 30 days. Find more at our full Returns Policy page.

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